<p class="abstract"><strong>Background:</strong> Fentanyl is a phenylpiperidine derivative synthetic opioid agonist. As an analgesic fentanyl is 75-125 times more potent than morphine. Sufentanil is a semisynthetic thienyl analogue fentanyl with analgesic potency 5 to 10 times more than that of fentanyl. Recently there has been an interest in using analgesics and local anaesthetics in an attempt to decrease the local anaesthetic dose enabling faster recovery.</p><p class="abstract"><strong>Methods:</strong> A double blinded randomised study was carried out with 50 patients of ASA grade I and II aged between 20 and 60 years undergoing elective inguinal and below inguinal region surgeries under low dose spinal anaesthesia. Patients received 10 mg of 0.5% hyperbaric bupivacaine with 50 μg of fentanyl added to a total volume of 3 ml (group F), and with sufentanil 5 μg [diluted with 5% dextrose] and volume made to 3 ml (group S). Postoperative VAS score for pain, duration of motor block and complications postoperatively is noted.</p><p class="abstract"><strong>Results:</strong> Prolonged postoperative analgesia was observed in group F (216.7 min) and group S (264.8) which was statistically significant among the groups (p<0.001) is higher in group S and also duration of motor block in group F (130.6) and group S (90.5) which was statistically significant among the groups (p<0.001) which is higher in group F than group S.</p><p><strong>Conclusions: </strong>When compared to intrathecal bupivacaine-fentanyl combination; intrathecal bupivacaine-sufentanil combination provided prolonged postoperative analgesia with a lesser duration of motor blockade thus allowing early post operative ambulation.</p>
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