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Considerable research on school vaccination laws and policies focuses on elementary, middle, and high school requirements. However, risks of infectious disease outbreaks are not limited to school-age children. Recent outbreaks of vaccine-preventable diseases (e.g., mumps and meningitis) among young adults at higher education institutions (e.g., university, college, and junior college campuses) have proliferated nationally. Collectively, they illustrate a pressing public health concern regarding low vaccination rates among higher education populations contributing to outbreaks of communicable diseases. A primary cause of these outbreaks is lax requirements for student vaccinations among higher education institutions as a requirement for matriculation.A series of inconsistences and failures concerning vaccination law or policy requirements among select higher education institutions lend to profound public health and ethical repercussions for students and community members. Against the backdrop of rising rates or outbreaks of vaccine-preventable conditions among institutional populations, addressing these findings is vital to alleviate future outbreaks on campuses and surrounding locales.