Speckle image Scattering Medium Coherent IlluminationMonte Carlo Rendering 0°0.0025°0.0075°g = 0 g = 0.9

Recent advances in computational imaging have significantly expanded our ability to image through scattering layers such as biological tissues by exploiting the auto-correlation properties of captured speckle intensity patterns. However, most experimental demonstrations of this capability focus on the far-field imaging setting, where obscured light sources are very far from the scattering layer. By contrast, medical imaging applications such as fluorescent imaging operate in the near-field imaging setting, where sources are inside the scattering layer. We provide a theoretical and experimental study of the similarities and differences between the two settings, highlighting the increased challenges posed by the near-field setting. We then draw insights from this analysis to develop a new algorithm for imaging through scattering that is tailored to the near-field setting by taking advantage of unique properties of speckle patterns formed under this setting, such as their local support. We present a theoretical analysis of the advantages of our algorithm and perform real experiments in both far-field and near-field configurations, showing an order-of magnitude expansion in both the range and the density of the obscured patterns that can be recovered.

approximations accelerate speckle rendering simulations by a few orders of magnitude compared to previous techniques, at the cost of negligible bias. We validate the accuracy of our algorithms by reproducing ground truth speckle statistics simulated using wave-optics solvers, and real-material measurements available in the literature. Finally, we use our algorithms to simulate biomedical imaging techniques for focusing through tissue.CCS Concepts: • Computing methodologies → Computational photography; Rendering.

Coherent images of scattering materials, such as biological tissue, typically exhibit high-frequency intensity fluctuations known as speckle. These seemingly noise-like speckle patterns have strong statistical correlation properties that have been successfully utilized by computational imaging systems in different application areas. Unfortunately, these properties are not well-understood, in part due to the difficulty of simulating physically-accurate speckle patterns. In this work, we propose a new model for speckle statistics based on a single scattering approximation, that is, the assumption that all light contributing to speckle correlation has scattered only once. Even though single-scattering models have been used in computer vision and graphics to approximate intensity images due to scattering, such models usually hold only for very optically thin materials, where light indeed does not scatter more than once. In contrast, we show that the single-scattering model for speckle correlation remains accurate for much thicker materials. We evaluate the accuracy of the single-scattering correlation model through exhaustive comparisons against an exact speckle correlation simulator. We additionally demonstrate the model's accuracy through comparisons with real lab measurements. We show, that for many practical application settings, predictions from the single-scattering model are more accurate than those from other approximate models popular in optics, such as the diffusion and Fokker-Planck models. We show how to use the single-scattering model to derive closed-form expressions for speckle correlation, and how these expressions can facilitate the study of statistical speckle properties. In particular, we demonstrate that these expressions provide simple explanations for previously reported speckle properties, and lead to the discovery of new ones. Finally, we discuss potential applications for future computational imaging systems.Index Terms-Scattering, Speckle statistics. ! îx,y = (0, 0) • (0, 0.2) • (0, 0.4) • (0, 0.6) •

Light propagating through a nonuniform medium scatters as it interacts with particles with different refractive properties such as cells in the tissue. In this work we aim to utilize this scattering process to learn a volumetric reconstruction of scattering parameters, in particular particle densities. We target microscopy applications where coherent speckle effects are an integral part of the imaging process. We argue that the key for successful learning is modeling realistic speckles in the training process. To this end, we build on the development of recent physically accurate speckle simulators. We also explore how to incorporate speckle statistics, such as the memory effect, in the learning framework. Overall, this paper contributes an analysis of multiple aspects of the network design including the learning architecture, the training data and the desired input features. We hope this study will pave the road for future design of learning based imaging systems in this challenging domain.