S63 and prevention age (until 5 years old), with a diagnosis of gastroenteritis (ICD-10th codes: A08 (viral and other intestinal infections), A09 (diarrhea and gastroenteritis of infectious origin)) from the National Health Insurance claims data. The annual prevalence rate of RVGE was calculated as the product of the number of gastroenteritis patients and the detection rate of RV among children with gastroenteritis under 5, retrieved from EnterNet, the national laboratory surveillance of acute gastroenteritis in Korea. The burden of RVGE was estimated from a restricted societal perspective including medical, non-medical and productivity loss costs due to morbidity. Annual national costs associated with RVGE were derived by multiplying the average cost per patient with RV-specific code (A08.0: rotaviral enteritis) by the estimated number of patients attributable to RV infection. All costs were expressed in 2015 US dollars (1 USD = 1,100 Korean won). RESULTS: Compared to pre-vaccination period, the prevalence rate constantly decreased in the post-vaccination period, implying an increase in the coverage rate of RV vaccination and in herd immunity. The prevalence rate of RVGE per 100,000 children fell from 5784.