A new concept for the optimization and optical design of miniature digital zoom optics with liquid lens elements is proposed in this research. The liquid lens elements are limited to the discrete configuration in order to obtain the optimal performance for digital zoom. We propose a newly developed digital zoom layout and optimization with a modified genetic algorism (GA) method, in order to meet the demands of a certain specification. The results show that we achieve a successful optical design and the optimization of the digital zoom optics with liquid optics, whose performance is greatly improved up to 48.68%, from the standpoint of on-axis spot size.