Cancer is a malignant disease that has caused millions of human deaths. Its study has a long history of well over 100years. There have been an enormous number of publications on cancer research. This integrated but unstructured biomedical text is of great value for cancer diagnostics, treatment, and prevention. The immense body and rapid growth of biomedical text on cancer has led to the appearance of a large number of text mining techniques aimed at extracting novel knowledge from scientific text. Biomedical text mining on cancer research is computationally automatic and high-throughput in nature. However, it is error-prone due to the complexity of natural language processing. In this review, we introduce the basic concepts underlying text mining and examine some frequently used algorithms, tools, and data sets, as well as assessing how much these algorithms have been utilized. We then discuss the current state-of-the-art text mining applications in cancer research and we also provide some resources for cancer text mining. With the development of systems biology, researchers tend to understand complex biomedical systems from a systems biology viewpoint. Thus, the full utilization of text mining to facilitate cancer systems biology research is fast becoming a major concern. To address this issue, we describe the general workflow of text mining in cancer systems biology and each phase of the workflow. We hope that this review can (i) provide a useful overview of the current work of this field; (ii) help researchers to choose text mining tools and datasets; and (iii) highlight how to apply text mining to assist cancer systems biology research.

Understanding the societal impacts caused by community disruptions (e.g., power outages and road closures), particularly during the response stage, with timeliness and sufficient detail is an underexplored, yet important, consideration. It is critical for effective decision-making and coordination in disaster response and relief activities as well as post-disaster virtual reconnaissance activities. This study proposes a semiautomated social media analytics approach for social sensing of Disaster Impacts and Societal Considerations (SocialDISC). This approach addresses two limitations of existing social media analytics approaches: lacking adaptability to the need of different analyzers or different disasters and missing the information related to subjective feelings, emotions, and opinions of the people. SocialDISC labels and clusters social media posts in each disruption category to facilitate scanning by analyzers. Analyzers, in this paper, are persons who acquire social impact information from social media data (e.g., infrastructure management personnel, volunteers, researchers from academia, and some residents impacted by the disaster). Furthermore, SocialDISC enables analyzers to quickly parse topics and emotion signals of each subevent to assess the societal impacts caused by disruption events. To demonstrate the performance of SocialDISC, the authors proposed a case study based on Hurricane Harvey, one of the costliest disasters in U.S. history, and analyzed the disruptions and corresponding societal impacts in different aspects. The analysis result shows that Houstonians suffered greatly from flooded houses, lack of access to food and water, and power outages. SocialDISC can foster an understanding of the relationship between disruptions of infrastructures and societal impacts, expectations of the public when facing disasters, and infrastructure interdependency and cascading failures. SocialD-ISC's provision of timely information about the societal impacts of people may help disaster response decision-making. 1 INTRODUCTION Disaster-induced community disruptions include physical infrastructure and social disruptions, such as hazards, lack of supplies, business interruption losses, and evacuation orders

Accurate quantification of drought characteristics helps to achieve an objective and comprehensive analysis of drought events and to achieve early warning of drought and disaster loss assessment. In our study, a drought characterization approach based on drought severity index derived from Gravity Recovery and Climate Experiment (GRACE) and its Follow-On (GRACE-FO) data was used to quantify drought characteristics. In order to improve drought detection capability, we used the local drought data as calibration criteria to improve the accuracy of the drought characterization approach to determine the onset of drought. Additionally, the local precipitation data was used to test drought severity determined by the calibrated drought characterization approach. Results show that the drought event probability of detection (POD) of this approach in the four study regions increased by 61.29%, 25%, 94.29%, and 66.86%, respectively, after calibration. We used the calibrated approach to detect the drought events in Mainland China (MC) during 2016 and 2019. The results show that CAR of the four study regions is 100.00%, 92.31%, 100.00%, and 100.00%. Additionally, the precipitation anomaly index (PAI) data was used to evaluate the severity of drought from 2002 to 2020 determined by the calibrated approach. The results indicate that both have a strong similar spatial distribution. Our analysis demonstrates that the proposed approach can serve a useful tool for drought monitoring and characterization.

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In this paper, we report our work on the flight recovery problem for China Eastern Airlines. Traditionally, the flight recovery problem is often modeled as an integer or mixed integer linear programming problem. However, such a model cannot take many complex constraints and uncertainties in real applications. Furthermore, we have found solutions obtained based on such a model difficult to implement in their existing operations, as in the case of CEA. Therefore, we propose a simulation-based approach, which works well with their existing operations. Our work demonstrates the potentials of simulation based methods in the study of the flight recovery problem, and possibly other similar problems.