Abstract2‐Alkynylaryl aldehydes are widely used in organic reactions. Their great success is rooted in their multiple functional groups. This review will focus on five kinds of triggered mechanisms: (i) aldehydes as electrophiles, (ii) alkynes as electrophiles, (iii) 5‐exo‐dig reactions, (iv) 6‐endo‐dig intermediates, and (v) imine intermediates via 6‐endo‐dig cyclizations. Reactions with alkenes, alkynes, arenes, malononitrile, alcohols, amines, amides, acetal, ketones, hydrazine, iodobenzene, azides, carbenes, arylboronic acids, amino acids etc. will be discussed. We hope that this review will pronote future research in this area.magnified image

Propargylamines are extremely versatile and common building blocks in the field of chemistry. This review highlights the recent advances made in the reactions of propargylamines between 2009 and 2019. The reaction types are classified into six categories based on the trigger mechanisms: (1) amino moieties as leaving groups, (2) hydrogenation, (3) rearrangement, (4) nucleophilic amines, (5) nucleophilic carbons, and (6) electrophilic alkynes. We hope that this review will promote future research in this area.1 Introduction2 Amino Moieties as Leaving Groups3 Hydrogenation4 Rearrangement5 Nucleophilic Amines6 Nucleophilic Carbons 7 Electrophilic Alkynes8 Conclusions