In the present study, we show novel data to suggest that simvastatin could suppress apoptosis in vulnerable atherosclerotic plaques of apoE(-/-) mice by regulating the expression of apoptosis-related proteins, such as p(53), Bcl-2 and Bcl-xL.

As China is one of the world’s most vulnerable countries to small and medium-scale natural hazards (SMNHs), its NGOs have had a great deal of experience in dealing with disaster relief, especially since the 2008 Wenchuan Earthquake; however, there have been few studies that have comprehensively examined China’s NGO disaster relief networks (NDRNs). One Foundation (OF), which is one of the most active public-fund raising foundations in China, has been engaged in developing a nationwide NDRN made up of 20 independently operating provincial networks that are focused on SMNHs. This paper explored the structures, operations and challenges in the representative North-Sichuan network, from which the following key factors for sustainable NDRNs were identified: (1) a combined hierarchal and networked organizational structure; and (2) a coordinated external and internal network operations mechanism that has a specific entry threshold to ensure healthy network expansion, periodic member NGO training to enhance network capacity, and reciprocal and cooperative government-NGO relationships. These findings provide a useful reference for the establishment and development of NDRNs in other countries.

As rural areas in developing countries are generally more vulnerable to disasters triggered by natural hazards than urban areas, it has become critical to strengthen rural community disaster resilience (CDR) to reduce the risks. Using follow‐up interviews, surveys, and secondary data, this study reviewed the Safe Rural Community (SRC) programme implemented by the One Foundation, a Chinese civilian non‐governmental organisation (NGO), after the 2013 Lushan earthquake in China. The study focused on five key resilience aspects: networks; infrastructure; institutions; capacity; and culture. It found that the SRC programme successfully developed five standardised, systematic, interrelated, and practical elements: localised volunteer rescue teams; adequate emergency supplies; practical disaster reduction training; community emergency plans; and regular emergency rescue drills. Third‐party evaluations and a 2022 Lushan earthquake test revealed that this NGO‐led, community‐based, and team‐oriented initiative had been effective. Consequently, the study provides some guidance for the development of effective CDR programmes in rural communities in developing countries.

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