Smart surfaces presenting both antifouling molecules with a charged functional group at their distal end, and molecules that are terminated by RGD peptides for cell adhesion, were fabricated and characterized (see picture). By applying potentials of +300 or -300 mV, the surfaces could be dynamically switched to make the peptide accessible or inaccessible to cells.
Mesoporous MnO2 nanosheet arrays have been directly grown on nickel foam current collectors and exhibited a reversible capacity as high as 1690 mA h g(-1) even after one hundred cycles at 100 mA g(-1). They also reveal good rate capability and excellent cycling stability.
Intelligente Oberflächen wurden hergestellt und charakterisiert, die zwei Arten von Molekülen tragen: anwuchsverhindernde Moleküle mit endständigen geladenen funktionellen Gruppen sowie Moleküle, die mit RGD‐Peptiden für die Zelladhäsion terminiert sind (siehe Bild). Durch Anlegen von Spannungen von +300 oder −300 mV konnten die Oberflächen zwischen zelladhäsiv und zellabweisend dynamisch geschaltet werden.
Humankind is generating digital data at an exponential rate. These data are typically stored using electronic, magnetic or optical devices, which require large physical spaces and cannot last for a very long time. Here we report the use of peptide sequences for data storage, which can be durable and of high storage density. With the selection of suitable constitutive amino acids, designs of address codes and error-correction schemes to protect the order and integrity of the stored data, optimization of the analytical protocol and development of a software to effectively recover peptide sequences from the tandem mass spectra, we demonstrated the feasibility of this method by successfully storing and retrieving a text file and the music file Silent Night with 40 and 511 18-mer peptides respectively. This method for the first time links data storage with the peptide synthesis industry and proteomics techniques, and is expected to stimulate the development of relevant fields.
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