Introduction: Dengue is the most prevalent viral mosquito-borne disease, with over 2.5 billion humans at risk given its endemicity in not less than 100 countries. Globally, 50-100 million cases of dengue is seen annually, with approximately 0.7% resulting in Dengue Hemorrhagic Fever (DHF), and 22,000 deaths. In 2017, there were 83,849 reported cases of dengue fever in endemic under-reported Malaysia, with 177 deaths. Method: The Authors here narrate from their own personal-experiences, besides reviewing existing-literature. Results and Conclusion: Prevention and Control methods have been desiring of greater achievements, but also show greater promise with Newer Insecticides, Innovative Methods and Vaccines. Dengue Fever would very likely become near-eradicated just like all other vaccine-preventable diseases, once comprehensive mass-vaccination programs are available globally, using safe and very-effective tetravalent-vaccines soon to be available.
Introduction: Dengue is the most prevalent viral mosquito-borne disease, with over 2.5 billion humans at risk given its endemicity in more than 100 countries. Globally, 50-100 million cases of dengue occur annually, with approximately 0.7% resulting in dengue haemorrhagic fever (DHF), and 22,000 deaths. In 2017, there were 83,849 reported cases of dengue fever in endemic under-reported Malaysia, with 177 deaths. One of our authors (Verasingam K 2006) here, earlier published an article in the Med J Malaysia titled “Dengue Fever in Malaysia: Time for Review?” This Article is meant as a sequel. Method: The Authors here narrate from their own personal-experiences, as well as from reviewing existing-literature. Results and Conclusion: Clinical Management has brought about vast improvements in mortality and morbidity. Similarly, great advancements in Laboratory Diagnostics. Prevention and Control methods have been desiring of greater achievements, but also show greater promise with Newer Insecticides, Innovative Methods and Vaccines. Dengue Fever would very likely become near-eradicated just like all other vaccine-preventable diseases, once comprehensive mass-vaccination programmes are available globally, using safe and very-effective tetravalent-vaccines soon to be available.
Introduction: In 1993, the International Task Force for Disease Eradication thought over and concluded that only six diseases are eradicable – but, malaria, dengue fever (and, dengue hemorrhagic fever) were not included. In 2010, 99 countries reported 219 million cases of malaria and 660,000 deaths. In Malaysia in 2011, 5152 cases had been reported causing not more than 30 deaths. Over 2.5 billion are at risk of dengue fever given the endemicity in excess of 100 countries, compared to nine countries in 1970. The WHO estimate 50-100 million cases annually globally, with approximately 500,000 dengue haemorrhagic fever, and an estimated 22,000 death each year. In Malaysia in 2017, there is found 83,849 reported cases of dengue fever with 177 deaths. There is a compelling need to give thought here to an elimination/eradication programme on dengue fever in Malaysia, realizing there is presently a malaria-elimination programme already. Aim: The Aim of this Review is to contemplate on the priority of possible public-health intervention of infectious-diseases, the International Task Force on Disease Eradication, and the three principle/indicators toward successful eradication/elimination programme, and the cost, beside describing the epidemiology and eradication/elimination of malaria in Malaysia, including the human and economic cost of malaria, in a comparison with dengue fever, including the dengue control & prevention programme and the potential in the innovative-methods, and why a dengue fever elimination programme is timely and imperative. Methodology: This article is a Narrative Review, and the author focus the article around three articles published by the author in recent times on dengue fever, and two on malaria. Additionally, the author contemplate around relevant newer article by various author retrieved through PubMed and Google Search. Results: Based on priority of possible public-health intervention of infectious-diseases by the International Task Force on Disease Eradication, and the principle/indicator(s) identified by the Task Force, and the Dahlem Conference, toward successful eradication/elimination programme, and the World Health Assembly on dengue fever, it is felt that a dengue fever elimination programme is timely and imperative, beside found very cost-beneficial. Conclusion: Mankind can eliminate dengue fever, even if not actually eradicating the disease, in a very much feasible and cost-beneficial programme, beginning in every nation and every region of the world, prior to grouping to become a global-programme.
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