Objective-Primary brain tumours may be associated with coagulation disorders which can pose intraoperative and postoperative management diYculties. The aim was to evaluate the coagulation profile of patients with brain tumours undergoing surgery using thromboelastography (TEG) in combination with simple laboratory tests.
Methods-Fifty
Triplets born to a Chinese woman consisted of 2 healthy boys and a girl with hemoglobin Bart’s hydrops syndrome. The girl with hemoglobin Bart’s hydrops syndrome, confirmed by gene analysis to be homozygous for α-thalassemia-1, survives for 27 months at the time of reporting. The dilemma in sustaining her life and the availability of other therapeutic options are briefly discussed. This is the third case report of homozygous α-thalassemia-1 with long-term survival.
Gelatinous transformation of marrow in a patient with acute myelogenous leukemia was reported. This case was at variance with other reported cases of gelatinous transformation of marrow in that a) it was associated with a primary bone marrow disease and b) there was no fat atrophy and the patient was not cachectic. The fact that it occurred abruptly post-chemotherapy suggested that marrow hypoplasia induced by chemotherapy could be the cause of this lesion in this particular situation.
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