PurposeActive exercise with compression therapy (AECT) is a standard treatment for gynecological cancer-related lower-limb lymphedema (LLL) in clinical situations. However, there is insufficient evidence regarding the immediate effects of the use of AECT on LLL. The purpose of this study was to evaluate the immediate effects of AECT on LLL.MethodsParticipants in this randomized controlled crossover trial comprised 23 women with LLL who completed high-load AECT, low-load AECT, and compression-only therapy (CT). AECT was performed on a bicycle ergometer with short stretch bandages. Each intervention was performed for 15 min, with successive interventions separated by a 1-week washout period. Lower-limb volume was assessed using a Perometer™ sensor (Pero-system, Wuppertal, Germany). General symptoms (pain and heaviness) and skin symptoms (pitting and stiffness) were assessed using a visual analog scale and palpation, respectively. Measurements were taken before and after each intervention. Analysis of variance using linear mixed-effect modeling was used for statistical analyses.ResultsVolume decrement differed significantly between all three interventions (P < 0.05). Lower-limb volume was significantly reduced after high-load AECT compared to that after CT. General symptoms and skin symptoms were similar across the three interventions, but severity of pre-intervention skin symptoms correlated significantly with volume decrement after high- and low-load AECT. High-load AECT using the bicycle ergometer was more effective than CT for decreasing lower-limb volume.ConclusionsThese results suggest that high-load AECT has marked effects on severe LLL.

12, Japan lron(ii1) complexes of general formula [ Fe(X) L]"+ ( n = 0 or 1 ) have been prepared and characterized, where X is a unidentate ligand such as CI-, N,-, NCO-, CN-, pyridine (py), 3met hy I pyrid i ne (3 Mepy ) , 4 -met h y I pyr id i ne (4 Mepy ) , 4 -am i no pyrid i ne (a py ) , 3,4dimethylpyridine (3,4Me2-py), imidazole (Him), N-methylimidazole (mim), or 2methylimidazole (2Me-im), and L denotes a quinquedentate Schiff base derived from salicylaldehyde and di(3-aminopropy1)amine. On the basis of the cryomagnetic data, these complexes can be classified into three groups: high spin ( S =+) for X = CI, N, , Him, mim; low spin (S =+) for) for X = py, 3Me-py, 4Me-py, 3,4Me2-py, 2Me-im. This indicates that the spin state for the series of complexes depends predominantly on the order in the spectrochemical series of the ligand X. The magnetic moments for the spin cross-over complexes increased gradually with increase of the temperature and showed no thermal hysteresis, indicating that the present complexes are of continuous spin-transition type. The spin cross-over complexes showed a thermochromism both in the solids and solutions, changing colour from dark violet to blue green, with decreasing temperature, and the thermochromism was studied by the temperature dependence of the electronic spectra in dichloromethane solution. The temperature dependence of the Mossbauer spectra for [Fe(2Me-im)L] BPh, and [Fe(4Me-py)L] BPh, has also provided evidence that the spin transition between the high-and low-spin states takes place and that the rate of spin interexchange is as fast as the inverse of the lifetime (1 x 1 O-' s) of the Mossbauer nucleus. One of the complexes, [Fe(4Me-py) L] BPh,, was also subjected to a single-crystal X-ray analysis. The result verified the detailed structure in which the iron( 111) atom assumes a pseudo-octahedral co-ordination geometry with a trans geometry for the two salicylideneiminate moieties, and the two axial positions are occupied by the secondary amine nitrogen of the di(3-aminopropy1)amine moiety of L and the nitrogen atom of the 4-methylpyridine ligand.

Five binuclear iron(III) complexes bridged by pyrazine, 1,1′-tetramethylenebis(imidazol), or bis(pyridine) compounds with the formula of [LFe(Bge)FeL](BPh4)2 have been prepared, and their spin-equilibrium behavior between high-spin(S=5/2) and low-spin(S=1/2) states has been investigated by means of the temperature dependences of the magnetic susceptibilities and the electronic spectra, where Bge denotes pyrazine, 1,1′-tetramethylenebis(imidazol), 4,4′-bipyridine, 4,4′-ethylenebis(pyridine), or 4,4′-vinylenebis(pyridine), L=bis(3-salicylideneaminopropyl)amine, and BPh4−=tetraphenylborate. The pyrazine complex is low-spin, while the bis(imidazole) and the bis(pyridine) complexes snowed a spin-equilibrium between high-spin and low-spin states, accompanied by a striking thermochromism in both the solids and solutions.

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Der asymm. vierzähnig koordinierte Cu(Il)‐Titelkomplex (Ia) reagiert genau wie seine Analogen (Ib)‐(Id) mit p‐Nitrobenzoldiazoniumtetrafluoroborat unter Bildung der substituierten p‐Nitrophenylazokomplexe (II).