Alterations in prostatic acid phosphatase (PAcP), a phosphotyrosyl phosphatase, corresponded to changes in overall tyrosyl kinase activity. PAcP added to extracts of prostate carcinoma cells with a low endogenous level of PAcP activity and elevated tyrosyl kinase activity decreased the tyrosyl kinase activity. On the other hand, when PAcP activity was decreased by the addition of androgens to cells, there was a corresponding increase in tyrosyl kinase activity.

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The physical implementation of a prototypical 250-MHz CMOS 4-T SRAM is described in this paper. The proposed SRAM cell takes advantage of a negative word-line scheme to minimize the leakage current of the cell access transistors. As a result, the standby power consumption is drastically reduced. The proposed 4-kb 4-T SRAM is measured to consume 0.32 mW in the standby mode, and a 3.8-ns access time in the R/W mode. The highest operating clock rate is measured to be 263 MHz.Index Terms-Leakage current, negative word-line (NWL), power-delay product, SRAM, 4-T SRAM cell.

No abstract