AbstractThe tibial tubercle–trochlear groove (TT–TG) distance was originally described for computed tomography (CT) but has recently been used on magnetic resonance imaging (MRI) without sufficient evidence demonstrating its validity on MRI. The current review aims to evaluate (1) whether there is a difference in the TT–TG distances measured using CT and MRI, (2) whether both the TT–TG distances measured using CT and MRI could be used to differentiate between patients with or without patellofemoral instability, and (3) whether the same threshold of 15 to 20 mm can be applied for both TT–TG distances measured using CT and MRI. The review was conducted using the preferred reporting items for systematic reviews and meta-analyses (PRSIMA) guidelines. All studies that compared TT–TG distances either (1) between CT and MRI or (2) between patients with and without patellofemoral instability were included. A total of 23 publications were included in the review. These included a total of 3,040 patients. All publications reported the TT–TG distance to be greater in patients with patellofemoral instability as compared to those without patellofemoral instability. This difference was noted for both TT–TG distances measured on CT and on MRI. All publications also reported the TT–TG distance measured on CT to be greater than that measured on MRI (mean difference [MD] = 1.79 mm; 95% confidence interval [CI]: 0.91–2.68). Pooling of the studies revealed that the mean TT–TG distance for the control group was 12.85 mm (95% CI: 11.71–14.01) while the mean TT–TG distance for patients with patellofemoral instability was 18.33 mm (95% CI: 17.04–19.62) when measured on CT. When measured on MRI, the mean TT–TG distance for the control group was 9.83 mm (95% CI: 9.11–10.54), while the mean TT–TG distance for patients with patellofemoral instability was 15.33 mm (95% CI: 14.24–16.42). Both the TTTG distances measured on CT and MRI could be used to differentiate between patients with and without patellofemoral instability. Patients with patellofemoral instability had significantly greater TT–TG distances than those without. However, the TT–TG distances measured on CT were significantly greater than that measured on MRI. Different cut-off values should, therefore, be used for TT–TG distances measured on CT and on MRI in the determination of normal versus abnormal values. Pooling of all the patients included in the review then suggest for 15.5 ± 1.5 mm to be used as the cut off for TT–TG distance measured on CT, and for 12.5 ± 2 mm to be used as the cut-off for TT–TG distance measured on MRI. The Level of evidence for this study is IV.

Background: Prescription audit is one of the methods to assess drug utilization and rationality of prescribing. Irrational prescribing is a worldwide problem. It is due to the faulty prescribing habits, lack of training amongst health care personnel, pressure from the pharmaceutical companies, and a lot of other reasons. Methods: The study was conducted by noting the details of patients admitted during 3 months from April to June 2015 in the Guru Gobind Singh Government Hospital, Jamnagar. Prescriptions were collected from the inpatients of medicine, surgery, obstetrics & gynecology, pediatrics, orthopedic randomly and analyzed according to the WHO core prescribing indicators. Results: Three hundred six prescriptions were analysed in which 1986 drugs were prescribed. Mean number of drugs per prescription was 6.49%. In our study, 63.34% drugs were prescribed by generic names and drugs on NLEM were 73.01%. Dosage forms used were mostly oral (69.54%). Infectious and parasitic diseases were the most common illnesses (16.01%) followed by diseases of respiratory system. The most common drug groups prescribed were GIT, antimicrobials, antihistaminics, multivitamins and minerals. The incidence of poly-pharmacy was also common with maximum number of prescriptions (26.8%) having 5 drugs per prescription. Conclusion: Prescription audit is an important measure to improve the quality of care afforded by the hospitals. Data generated on morbidity pattern coupled with current practices of treatment of these diseases provides an objective basis for preparing an NLEM. By this data we conclude that poly-pharmacy is quite common. Most of drugs were prescribed according to the NLEM 2011.

Introduction: Treatment of proximal humerus fractures always holds a dilemma for the treating surgeon.

Cerebral palsy (CP), a heterogeneous disorder of movement and posture, is one of the most important causes of disability affecting children. With a wide variability in the clinical presentation and a paucity of reliable diagnostic tests, decision-making in CP is fraught with difficulties and challenges. The plethora of musculoskeletal manifestations includes poor muscle function, spasticity, rigidity, muscle weakness, poor selective motor control, soft-tissue and joint contractures, torsional malalignments, and lever arm dysfunctions. Children with CP are at a high risk of further worsening and progression of these musculoskeletal abnormalities with the natural course of the disease. A comprehensive assessment that includes a combination of detailed medical history, functional assessment, clinical examination, analysis of gait, and radiological assessment is required to provide a favorable treatment outcome in these children. A close surveillance is essential so as to identify risk factors for the development and progression of musculoskeletal problems so that early interventions can be carried out to circumvent them. This review article is to highlight the importance of clinical examination in the assessment of children with CP.

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