Catalytic reduction reactions using methanol as a transfer
hydrogenating
agent is gaining significant attention because this simple alcohol
is inexpensive and produced on a bulk scale. Herein, we report the
catalytic utilization of methanol as a hydrogen source for the reduction
of different functional organic compounds such as nitroarenes, olefins,
and carbonyl compounds. The key to the success of this transformation
is the use of a commercially available Pt/C catalyst, which enabled
the transfer hydrogenation of a series of simple and functionalized
nitroarenes-to-anilines, alkenes-to-alkanes, and aldehydes-to-alcohols
using methanol as both the solvent and hydrogen donor. The practicability
of this Pt-based protocol is showcased by demonstrating catalyst recycling
and reusability as well as reaction upscaling. In addition, the Pt/C
catalytic system was also adaptable for the N-methylation
and N-alkylation of anilines via the borrowing hydrogen
process. This work provides a simple and flexible approach to prepare
a variety of value-added products from readily available methanol,
Pt/C, and other starting materials.
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