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Genitourinary Tuberculosis (GUTB) is a common manifestation of tuberculosis and usually results from the reactivation of old, dormant tuberculous diseases by pathogens of the Mycobacterium tuberculosis complex. Most often, GUTB has a varied presentation ranging from irritative voiding symptoms to renal failure. Due to this varied presentation, diagnosis of GUTB is often very difficult. We present a case of a reproductive-age female with asymptomatic infertility. Many diagnostic measures failed to identify the root cause of her infertility, however the positive PPD test was the first indicator of a possible reactivation of tuberculosis and histopathological examination of the tissue confirmed the diagnosis. We describe the definitive measure used to diagnose GUTB and the improvement of her infertility after anti-tubercular medications.

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