The COVID-19 pandemic is a global health crisis that severely influences humanity and the well-being of the planet. Countries and international health organizations implemented distinct protocols during the spread period of COVID-19, in efforts to control the spread of the pandemic. Before protocols are implemented, risk communication occurs as a foremost connection between the pandemic and the public. Public efforts and attention are important factors in further establishing specific protocols for them to work successfully. After risk communication, protocols such as quarantine, isolation, contact tracing, and social distancing, are implemented to control the spread of COVID-19. Each protocol contains specific advantages but also certain shortcomings that can be improved with future research. All can harm the well-being of individuals in some particular way, which needs to be improved. The spread period takes in protocols generated by the efforts of multiple parties, in order to reach the ultimate goal of returning to normal life.