Introduction The term ‘occupational profile’ is widely used within the occupational therapy profession; however, its use and application appear inconsistent in the literature. Understanding how occupational profile is described in existing literature can reduce ambiguity and strengthen consistent use of terminology across practice and research. Methods A scoping review was conducted to examine how occupational profile has been described in occupational therapy and occupational science literature. Results Seventy-six journal papers were included. A lack of consistent definitions, conceptualisation and measurements was identified. Key concepts relating to the conceptualisation of occupational profile included occupational history, motivation and performance. Only one measurement was used consistently with paediatric clients to identify individuals’ occupational profiles. Occupational profiles of populations and communities were not identified. Conclusion The lack of consistency in definitions, conceptualisation and measurement of the term ‘occupational profile’ presents significant issues for occupational therapy practice, including an inability to compare populations. Researchers should articulate their conceptualisation of occupational profile in the absence of a universally agreed-upon definition. More comprehensive measures seeking to explore the occupational profile of a variety of clients need to be developed. Occupational profiles of communities and populations should be explored to understand occupational patterns and identify potential occupational issues.