Enhancing medication adherence of patients can lead to lowering the morbidity, mortality, and the healthcare cost. Throughout the years of research, multiple interventions were created to help improve the medication adherence of the patients. However, it is still difficult for some developing countries, including the Philippines that need further guidance to strengthen their healthcare system. The goal of this review article is to gather information on the different interventions to improve medication adherence of patients with chronic diseases around Asia. Results should focus and suggest ways on improving the healthcare system of the Philippines in dealing patient with chronic diseases.