Twenty patients with symtomatic congenital cysts in the liver. kidney. thyroid. and lower n eck underwe nt. ultrasound guided percutaneous aspiration through a dra inage catheter with te mporary instillation of 95% ethanol into the cyst . Our procedure was based on the method as described by Bean and Rodan(16l in 1985. Additionaly. two othe steps were odded to prevent the dilutional effect of residual cyst fluid . One was the preliminary washing of th e cyst with alcohol. The other was to treat with 30% replace m e nt of alcohol every 10 minutes during the treatm ent secession. Minor complications of transie nt temperature e levation and haziness occurred . butj no major complications were encountered.After the alcohol treatmen t follow up examinations were performed with computed tomography or ultrasonography a t 6 wee ks. 6 months. 9 months a nd 15 months. Although there was diminished size. recurrence was noted in 6 of twenty patients(30%l at 6 weeks and one of twenty patients(5%l at 6 months. There was no recurrence at 9 months a nd 15 months.The results indicated that perc utaneous aspiration a nd alcohol sclerotherapy are safe and effective the rapy for symptomatic congenital cysts.

To evaluate a new reliable sclerosant of the gallbladder. we attempted gallbladder ablation with 10% phenol. and the resu 1ts compared with those from using 95% ethanol which had been used previousy as gallbladder sclerosing agent in laboratory animals in other re ports. After lapa rotomy , ligation of the cystic ducts with silk and cannulation of gallbladder with 18 gauge angiocath eter were done. Then , transcatheter administration of two differe nt scleroing agents w as performed in 8 rabbits resp ectively and norma l saline in four rabbits as a control. Additionally, preliminary washing with each agent were implemented to prevent the dilutional effect of residual bile and bleeding All animals survived without complication. Eight a nimals were used for each agent, four each being sacrified two wee ks a nd six weeks after adminstration of sclerosing agents respectively. In our results , 10 % phenol was more effective than 95 % ethanol in denuding the gallbladder epithelium and promoting fibrosis of gallbladder wall. And it was relatively safe in regard to the dilutional effect of residual fluid and bleeding during procedure. Toxic effects on the liver evaluated by examination of histologic specimen were non-specific except for e dematous swelling on some cases, which had a lso been observe d on others including control group .10% phenol can be considered to be a promosing sc1erosant for gallbladder a blation, but furth e r study of its toxicity is needed before its application on human gallbladder.