Bacteremia is common with manipulation of the teeth and periodontal tissues during dental procedures. Majority of dental office visits result in some degree of bacteremia that warrants antibiotic prophylaxis before a dental procedure to reduce the frequency, nature or duration of bacteremia. This study aimed to collect data on prophylactic use of cephradine which is most preferred in dental procedures in Bangladesh. A total 2219 of patients both adult and children above 5 years were enrolled to assess use of antibiotic, its dose and duration for antibiotic prophylaxis during dental procedures. Efficacy of antibiotic prophylaxis in terms of clinical cure, further dose modification and need to change antibiotic was evaluated at day 10 of antibiotic use and in case of root canal therapy at day 30. Any side effect of antibiotic use recorded within 3 days was considered for safety evaluation. This was a non-controlled, multicentre, observational study. 2016 (90.9%) of the patients received cephradine as prophylactic antibiotic with a mean dosage of 500mg (487.48+60.99) and duration of treatment was 3-7 days (5.47+1.03). Some of the dentists also preferred amoxicillin (149, 6.7%) and cephalexin (54, 2.4%) for prophylaxis. The majority of the patients (1657, 82.2%) who had prophylaxis with cephradine had no clinical sign of infection and some of the patients needed to change their initial dose or change of the antibiotic. Overall 1816 (81.8%) patients were found having no clinical sign of infection on antibiotic prophylaxis. Among the patients 239 (10.7%) needed to change the dose of prescribed antibiotic and 55 (2.4%) were required to change their prescribed antibiotic. However, the data on type of infection was not recorded. 109 (4.9%) patients were lost to follow up on Day 10. Prescribed antibiotic prophylaxis was not associated with adverse events in majority (91%) of the patients. Some of the patients reported diarrhea (104, 4.7%), stomach upset (68, 3.1%) and dizziness (31, 1.4%) during antibiotic use. However, those were self-limiting and no dose adjustment, discontinuation of therapy or withdrawal from the study was required. No serious adverse events were reported. Cephradine 500 mg for 5 days course was preferred as prophylactic antibiotic in dental procedures in this study. Majority of the patients had no clinical sign of infection on evaluation at day 10. Cephradine therapy was mostly not associated with adverse events in patients; however, diarrhea, stomach upset and dizziness were reported in some patients that were self-limiting.Bangladesh Journal of Dental Research and Education Vol.5(2) 2015: 49-54
Human teeth are among the most distinctive and long lasting features of mammal species. Various quantitative and qualitative methodologies have been developed by the researchers in order to establish an assessment format to determine the correlation between the dental age and the chronological age. The morphological and radiological examinations of third molars make up a part of the orthodontic, pedodontic, forensic odontology and oral surgical treatments and remain the most reliable biologic indicator available for age estimation during the middle teens and early twenties. This age calculation requirement is not only for differentiating the juvenile from the adult status in criminal law cases, but also for chronological age estimation in relation to school attendance, social benefits, employment and marriage. A case for actual need for age estimation using a developing third molar is presented here DOI: http://dx.doi.org/10.3329/bjdre.v5i1.22456 Bangladesh Journal of Dental Research and Education Vol.5(1) 2015: 22-25
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.