The stress of caring for a loved one with chronic illness has been linked with impairments in cognitive processes such as attention and problem solving, though few studies have examined the impact on memory. Compromised cognition, in particular, aspects of everyday functioning such as remembering medical instructions and appointments, might affect caregivers' ability to maintain the consistency and quality of care needed by the child. A sample of 31 caregivers of children with autism and 51 parents of neuro-typical children completed an electronic survey assessing levels of psychological distress and everyday memory. Data confirmed that perceived levels of stress and memory failures for everyday tasks were higher in caregivers compared with the control group. Data also revealed a significant positive relationship between caregivers' perceived levels of stress and everyday memory failures. These findings might have implications for interventions that aim to improve caregivers' cognitive well being through targeting the psychological sequelae associated with the caregiving experience.