Stress urinary incontinence (SUI) consists a clinical entity affecting approximately 1/3 of women worldwide. Therefore, management and therapeutic mapping should be planned assiduously. Surgical treatment for SUI has been an optimal surgical intervention for over 50 years, beginning from Burch colposuspension and Kelly’s plication, to midurethral slings, tension free vaginal tapes, trans obturator tapes and autologous fascial slings. Even though synthetic midurethral slings represented the most common surgical approach since the mid 90’s, due to their minimally invasive character, nowadays, lots of concerns have been raised among medical community concerning their serious long-term complications such as, mesh erosion, vaginal extrusion, urethral erosion and injury, groin, thigh or pelvic pain, recurrent infections and dyspareunia. These complications forced FDA (Food and Drug Administration) to issue a warning against their use, leading the implementation concerning autologous facial slings come back in to the surface. Despite the fact that the use of autologous fascial slings depicts a more invasive and challenging approach to treat SUI, there are notably more benefits regarding postoperative outcome, as well as decreased rate of potential complications when compared to TVT (Tension-free Vaginal Tape) and TOT (Trans Obturator Tape). Although, more trials and data must be conducted in order to be considered as main approach. Aim of this analytic review consists efficacy’s depiction of the autologous fascial slings according to recent bibliography and the role they could play in the near future concerning optimal therapeutic strategy of SUI.
Sphingomonas paucimobilis represents an aerobic Gram-negative bacillus that is gaining recognition as an important human pathogen. These species are widely distributed in both natural environment and hospitals. They appear as opportunistic pathogen that take advantage of underlying conditions and diseases. Regardless of the clinical significance, pathogenic mechanism varies throughout current bibliography. Aim of our study, reflects presentation of a rare case of an out-patient clinical asymptomatic, with vaginal culture positive for this rare microorganism, S. paucimobilis. Assiduous diagnosis and therapeutic mapping consist necessary conditions of effective treatment.
Preoperative distinction between benign and malignant pelvic mass plays an important role in treatment planning ultimately based on the patient's survival rate and quality of life.The ROMA (Risk of Ovarian Malignancy Algorithm) predictor uses a combination of HE4 (Human Epididymis protein 4) and CA125 to assess the risk of ovarian epithelial cancer (EOC) in women with established pelvic mass.It represents a useful algorithm with significant diagnostic value in detecting ovarian epithelial processes in postmenopausal women, but not in premenopausal patients.In addition, the very high specificity of HE4 in distinguishing endometriosis and benign ovarian cysts from EOC is emphasized. As in the case of Ca 125 is not a clinical means of utilizing population control (screening test). Increased can be found in other clinical cases, a condition that requires thorough clinical laboratory testing and accurate differential diagnosis. Aim of this study reflects the determination of usefulness of ROMA marker in the preoperative categorization of patients with ovarian processes at high and low risk for ovarian epithelial carcinoma (EOC).Criteria for excluding these studies are established malignancy in both the minor pelvis and the systemic circulation, as well as the existence of systemic diseases.
Vulnerability to breast cancer development is indirectly linked with pregnancy.[4] Estrogens, prolactin, progesterone, insulin-like growth factor -I(IGF-1), are hormonal examples which influence the breast neoplasmatic cell stimulation , in cases of undetectable and predominant lesions.Family history and genetic predisposition (mutation of Br-Ca 1 and Br-Ca 2) consist the most significant
Endometrial cancer represents the second most frequent malignant entity among gynecologic malignancies. Many predisposition factors reflect and affect the chronical outcome of the lesion. Age of the patient, obesity, postmenopausal vaginal bleeding among with endometrial hyperplasia, histologic type, grading, staging, vascular or lymph node penetration consist factors with direct depiction concerning the therapeutic mapping. Sentinel node consists the first regional lymph node infiltration, indicating local or external spread of the lesion. In order to explore and investigate potential infiltration or metastatic capability of the lesion, sentinel mode infiltration represents optimal solution. According to current bibliography, sentinel node infiltration depicts increased sensitivity and specificity concerning surgical or conservative therapeutic management. Aim of our study represents assiduous decoding of sentinel node infiltration and potential metastatic pathways, with ultimate scope the increased optimal survival and quality of life of the patient.
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