Closed quantum many-body systems out of equilibrium pose several long-standing problems in physics. Recent years have seen a tremendous progress in approaching these questions, not least due to experiments with cold atoms and trapped ions in instances of quantum simulations. This article provides an overview on the progress in understanding dynamical equilibration and thermalisation of closed quantum many-body systems out of equilibrium due to quenches, ramps and periodic driving. It also addresses topics such as the eigenstate thermalisation hypothesis, typicality, transport, many-body localisation, universality near phase transitions, and prospects for quantum simulations.Comment: 7 pages, review and perspectives article, updated to journal version after embarg

We review selected advances in the theoretical understanding of complex quantum many-body systems with regard to emergent notions of quantum statistical mechanics. We cover topics such as equilibration and thermalisation in pure state statistical mechanics, the eigenstate thermalisation hypothesis, the equivalence of ensembles, non-equilibration dynamics following global and local quenches as well as ramps. We also address initial state independence, absence of thermalisation, and many-body localisation. We elucidate the role played by key concepts for these phenomena, such as Lieb-Robinson bounds, entanglement growth, typicality arguments, quantum maximum entropy principles and the generalised Gibbs ensembles, and quantum (non-)integrability. We put emphasis on rigorous approaches and present the most important results in a unified language.