Head or neck location of primary cutaneous melanomas has been described as an adverse prognostic factor, but this has to be reassessed after the introduction of sentinel lymph node (SLN) excision (SLNE). Descriptive statistics, Kaplan-Meier estimates and Cox proportional hazard models were used to study retrospectively a population of 2302 consecutive melanoma patients from three German melanoma centres undergoing SLNE. Approximately 10% of the patients (N=237) had a primary melanoma located at the head or neck (HNM). In both the SLN-positive and SLN-negative subpopulation, patients with HNM were significantly older, more frequently men and had thicker primaries compared with patients with tumours in other locations. The proportion of positive SLNs was lower in HNM compared with other locations of the primary (20 vs. 26%, P=0.048). The false-negative rate was higher in HNM (17.5 vs. 8.4%, P=0.05). In patients with HNM, the SLN status was a significant factor for recurrence-free survival but not for overall survival. SLN-negative HNM patients had a significantly worse overall survival than the SLN negatives with primaries at other sites, whereas the prognosis of the SLN-positive patients was similar in both groups. The prevalence of lymph node metastases after SLNE is lower in patients with HNM compared with other melanoma locations. As a result, the prognostic information provided by the SLN for HNM seems less important. Decision making for SLNE in HNM should be carefully balanced considering the potential morbidity of the procedure.
Aims: To analyze frequency distribution of prosthetic reconstructions and therapeutic modalities with implant-supported reconstructions (ISRs) applied in a university graduate program. Methodology: Data of implant placement and related ISR were obtained from treatment plans, surgical protocols and patients' charts, covering the 2005 to 2010 time period. Loading time, implant survival and type of ISR, i.e. fixed (single crown (SC), short-span fixed dental prosthesis (FDP), full-arch FDP (IB)) and removable ISR (denture with ball attachments (RDP), bar-supported overdenture (Bar-IOD)) were determined and analyzed with descriptive statistical methods. Results: Data of 819 patients with a mean age of 62.3 ± 11.6 years were available. Graduate students placed 2337 implants and 1133 related ISRs were fabricated. The observation time ranged from 1 to 8 years (mean 4.7 ± 1.8). The number of implants supporting fixed and removable ISRs was 1053 (45.1%) and 1284 (54.9%), respectively. The percentage distribution of implants per ISRs exhibited 337/337 SCs (14.4%), 422/190 FDPs (18.1%), 294/54 IBs (12.6%), 374/198 RDPs (16.0%) and 910/354 Bar-IODs (38.9%). Thirty-one implants were lost (12 before and 19 after loading) resulting in an 8-year cumulative survival rate of 98.6% without difference between implants of different groups (fixed vs. removable ISRs, splinted vs. non-splinted ISRs, no GBR/SFE vs. GBR/SFE, upper vs. lower jaw). Conclusions: A broad variety of fixed and removable implant supported prostheses for partially and completely edentulous patients was identified. Although these data represent learning curves for graduate students working under supervision, implant survival was successful in a short-term range.
When meeting someone at zero acquaintance, we make assumptions about each other that encompass emotional states, personality traits, and even cognitive abilities. Evidence suggests individuals can accurately detect psychopathic personality traits in strangers based on short video clips or photographs of faces. We present an in-depth examination of this ability. In two studies, we investigated whether high psychopathy traits are perceivable and whether other traits affect ratings of psychopathic traits in the sense of a halo effect. On the perceiver’s end, we additionally examined how cognitive abilities and personality traits of the responders affect these ratings. In two studies (n1 = 170 community adults from the USA, n2 = 126 students from Australia), participants rated several targets on several characteristics of psychopathy, as well as on attractiveness, masculinity, sympathy, trustworthiness, neuroticism, intelligence, and extraversion. Results show that responders were generally able to detect psychopathy. Responders generally came to a consensus in their ratings, and using profile similarity metrics, we found a weak relation between ratings of psychopathy and the targets’ psychopathy level as determined by the Psychopathy Checklist: Short Version. Trait ratings, though, were influenced by the ratings of other traits like attractiveness. Finally, we found accuracy in the perception of psychopathy was positively related to fluid intelligence but unrelated to emotion perception ability.
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