Cryopreserved homograft dysfunction is frequent and progressive. Young age at operation (< 18 months) predicts more rapid deterioration. Doppler echocardiography is reliable in assessing the systolic gradients across homografts. Serial echocardiographic assessment in the follow-up of these patients accurately characterizes these problems.

Patients with orthostatic test-proved neurocardiogenic syncope show evidence of autonomic dysfunction. They also show beta-adrenergic hypersensitivity. Treatment initiated on the basis of the protocol was associated with amelioration of symptoms in the majority of patients.

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There are several perfusion techniques that can contribute to blood conservation. Minimizing existing circuit components, using mini-circuits and the maneuver of retrograde autologous priming can be considered steps in prime reduction. Microplegia systems may also reduce systemic as well as cardiac hemodilutional effects. Cell savers can scavenge shed blood, wash the red cells, and may return the red cells to the patient in a concentrated form. When a patient is already hemodiluted, ultrafiltation can be used to hemoconcentrate the patient and to drive their existing hemoglobin levels up. Ultimately, the optimal form of blood conservation comes from team-work, communication, and a combination of efforts.

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