AimsThe aim of this study was to provide recommendations for training patients with hereditary angioedema, based on nursing clinical trial experience, to self‐administer subcutaneous C1‐INH (C1‐INH[SC]) used as routine prophylaxis.BackgroundA volume‐reduced, subcutaneous C1‐INH concentrate (C1‐INH(SC); HAEGARDA®; CSL Behring) was recently FDA‐approved for the routine prevention of hereditary angioedema attacks. Nurses will play an important role in patient training.DesignReview of a phase 3, randomized, placebo‐controlled, double‐blind, crossover trial of C1‐INH(SC) (COMPACT) and summary of recommendations for training patients based on nurses’ “hands‐on experience.”MethodsA panel of nurses with clinical trial experience provided recommendations for patient training.ResultsPractical suggestions and guidelines were compiled regarding patient selection, product reconstitution and administration and patient follow‐up. Successful patient self‐administration of C1‐INH(SC) can be greatly facilitated by qualified nursing intervention. The information provided in this paper will be useful to nurses anywhere who have an opportunity to interact with patients dealing with hereditary angioedema.
Despite rapidly growing interest in Hospital Medicine
(HM), no prior research has examined the factors that
may be most beneficial or detrimental to candidates
during the HM hiring process. We developed a survey
instrument to assess how those involved in the HM
hiring process assess HM candidate attributes, skills
and behaviors. The survey was distributed electronically
to nontrainee physician Society of Hospital Medicine
members. Respondents ranked the top five qualifications
of HM candidates and the top five qualities an HM
candidate should demonstrate on interview day to
be considered for hiring. In thematic analysis of freeresponse
questions, several themes emerged relating
to interview techniques and recruitment strategies,
including heterogeneous approaches to long-term versus
short-term applicants. These findings represent the
first published assessment in the area of HM hiring and
should inform HM candidates and their mentors.
As NPs play an increasingly vital role in primary care, they must be well versed in a variety of conditions. Alpha-1 antitrypsin (AAT) deficiency is a respiratory disease for which there is particularly low awareness in both the nursing profession and the wider medical community. This article provides an overview of AAT deficiency and includes guidance for diagnosing the disease.
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