Melinjo (Gnetum gnemon L.) or in Sundanese is known as "Tangkil, " is a species of Gnetum (Gymnospermae) native to tropic Asia, Melanesia, and West Pacific. Melinjo seeds have been consumed by the community as vegetables and as a snack in the form of Melinjo chips. The seed was reported to demonstrate some pharmacological activity, such as antioxidants, 1 anticancer, 2 anti-coagulant, 3 hyperuricemia, 4 HMG-CoA reductase, 5-6 anti-obesity, 7 an d angiotensin-converting enzyme inhibitory. 8 The seeds are rich-in stilbenes, such as resveratrol, which occurs as two isomers: cis-resveratrol and trans-resveratrol. Both isomers have different biological activity (such as antioxidant, HMG-CoA reductase, antihypertension, and so on). However, effects produced by trans-resveratrol are stronger than the results produced by cis-resveratrol. 9-10 It has also been found that resveratrol stability is affected by light and high temperatures. 11 In Indonesia culinary practices, Melinjo seeds are often as snack food ingredient and are processed into sundried, flat cakes called emping, which are fried in cooking oil before consumption. 12 The seeds are also consumed as an additional ingredient
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