Our data suggest that P. aeruginosa ST235 (a) has become prevalent across the globe potentially due to the selective pressure of fluoroquinolones and (b) readily became resistant to aminoglycosides, β-lactams and carbapenems through mutation and acquisition of resistance elements among local populations.

The treatment at the WWTP led to the relative enrichment of ESBLEC. We estimated that >600 billion of ESBLEC are released into the river Doubs daily and the sludge produced by the WWTP, used as fertilizer, contains 2.6 × 10(5) ESBLEC per gram.

Abstract-Traditionally, chaotic systems are built on the domain of infinite precision in mathematics. However, the quantization is inevitable for any digital devices, which causes dynamical degradation. To cope with this problem, many methods were proposed, such as perturbing chaotic states and cascading multiple chaotic systems. This paper aims at developing a novel methodology to design the higher-dimensional digital chaotic systems (HDDCS) in the domain of finite precision. The proposed system is based on the chaos generation strategy controlled by random sequences. It is proven to satisfy the Devaneys definition of chaos. Also, we calculate the Lyapunov exponents for HDDCS. The application of HDDCS in image encryption is demonstrated via FPGA platform. As each operation of HDDCS is executed in the same fixed precision, no quantization loss occurs. Therefore, it provides a perfect solution to the dynamical degradation of digital chaos.