IntroductionThe DASS is a self administered questionnaire which principally measures anxiety stress and depression as a feature of the general population with 42 items.AimsTo create an easy to use and valid measurement, for primary care and during treatment assessment in patients with anxiety or depression disorders.MethodsTranslation was performed using the multiple forward and backward translation protocol. STAI state and trait along with BDI were also administered to check construct validity of DASS.Results537 adults participated, 178 (33.6%) male, 349 (64.6%) female. The total scale of the DASS-42 had a coefficient alpha of .968. Subscale coefficient alphas also were high (αdepression = ,941; αanxiety = ,906 ; αstress = ,942). Mean score for stress was 12,46 (SD = 9,82), for anxiety 7,19 (SD = 7,7) and for depression 8,05 (SD 9,6). Both subscales and total score were significantly correlated with STAI and BDI (r = .60 to.73, p < .01).Principal Components Analysis revealed the presence of 3 factors explaining 56% of the total variance. 14 items loaded in the stress subscale, 14 in the depression factor, but only 12 in the anxiety factor. ANOVAs found significant differences in all subscales between healthy adults and psychiatric outpatients. (p < ,001).ConclusionsThe results of the current validation study suggest that the Greek translation of the DASS is both reliable and valid, with psychometric properties close to those reported in the international literature.

The simultaneous estimation of three noninvasive indexes of arterial stiffness leads to valuable information regarding their association with TOD including CFR, MAU levels, IMT, left ventricular diastolic dysfunction, and LA enlargement in never-treated hypertensive patients regarding their dipping status.

Impaired cognitive function is associated with increased large artery stiffness and microalbumin excretion in newly diagnosed, untreated hypertensive patients. These findings support the hypothesis that cognitive impairment induced by impaired microcirculation is linked to large artery stiffness and microvascular damage.