Introduction: The goal of drug treatment for chronic obstructive pulmonary disease (COPD) is to relieve symptoms and lower the chance of future problems like flare-ups, disease progression, and death. Because COPD is not all the same, people respond differently to drug treatments. The best way to treat COPD now is with precision medicine, which uses clinical and biomarker data to make treatment decisions that are best for each person. The aim: This article discusses management of stable chronic obstructive pulmonary disease. Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: In the PubMed database, the results of our search brought up 68 articles, whereas the results of our search on SagePub brought up 32 articles. The results of the search conducted for the last year of 2013 yielded a total 31 articles for PubMed and 15 articles for SagePub. In the end, we compiled a total of 14 papers, 10 of which came from PubMed and four of which came from SagePub. We included four research that met the criteria. Conclusion: COPD treatment has evolved to match clinical characteristics and biomarkers to each patient. Hospitalizations and death have improved in triple combination treatment studies.  However, COPD treatments are lacking, such as emphysema-slowing drugs. Despite progress, much remains.

Introduction: Achieving glycemic control remains difficult for patients with type 1 diabetes. We compared the efficacy of day-and-night hybrid closed-loop insulin delivery to sensor-augmented pump therapy in individuals 6 years and older with suboptimally controlled type 1 diabetes. The aim: This article compared effectiveness and safety of methods of insulin delivery and glucose monitoring for diabetes mellitus. Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: In the PubMed database, the results of our search brought up 166 articles, whereas the results of our search on SagePub brought up 143 articles. The results of the search conducted for the last year of 2013 yielded a total 116 articles for PubMed and 89 articles for SagePub. In the end, we compiled a total of 23 papers, 15 of which came from PubMed and eight of which came from SagePub. We included six research that met the criteria. Conclusion: The use of a hybrid closed-loop insulin delivery system in free-living conditions for a period of twelve weeks led to clinically relevant improvements in glycaemic control while simultaneously reducing the risk of hypoglycemia in suboptimally controlled type 1 diabetes in adults, adolescents, and children aged six years and older.

Introduction: Due to DM diagnosis criteria, determining its incidence is difficult. Diabetes affects 10.2 million Americans.  Due to conflicting data on mortality and antihyperglycemic therapy benefits, managing hyperglycemia in type 2 diabetes mellitus (T2DM) patients at risk of cardiovascular problems is difficult. The aim: This article showed about metformin is Linked to reduced mortality in type 2 diabetes with comorbid chronic kidney disease (CKD) and congestive heart failure (CHF). Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: In the PubMed database, the results of our search brought up 85 articles, whereas the results of our search on SagePub brought up 57 articles. The results of the search conducted for the last year of 2013 yielded a total 34 articles for PubMed and 21 articles for SagePub. In the end, we compiled a total of 19 papers, 13 of which came from PubMed and seven of which came from SagePub. We included five research that met the criteria. Conclusion: Metformin use was found to be related with a reduced risk of death from any cause as well as progression toward ESRD in patients with CKD and CHF in the current investigation.

Introduction: Pneumonia is an inflammation of the lung parenchyma in the distal terminal bronchioles, which includes the respiratory bronchioles and alveoli. Corticosteroids are routinely used for severe pneumonia symptoms. Numerous studies on adjuvant corticosteroids for community-acquired pneumonia (CAP) have yielded equivocal results. Several systematic reviews and meta-analyses have studied the efficacy of corticosteroids in treating CAP. The aim: This article showed about corticosteroid therapy for patients hospitalized with community-acquired pneumonia (CAP). Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: The PubMed database yielded a total of 423 articles in response to our search query, while the search conducted on SagePub retrieved 491 articles. The search run for the last year of 2013 generated a total of 223 articles from PubMed and 212 articles from SagePub. Ultimately, a cumulative sum of 21 scholarly articles was assembled, with 15 originating from the PubMed database and the other six sourced from SagePub. We have incorporated four studies that satisfied the specified criteria. Conclusion: Administration of steroids as early as possible in patients with severe CAP who are treated to benefit, where they do not experience therapy failure. Slower administration and inadequate doses do not provide any benefit.

Introduction: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is possible that behavioral programs can improve outcomes for people living with type 2 diabetes mellitus; however, there is a huge variety of behavioral interventions to choose from, and it is unclear how to maximize the efficacy of these programs. The aim: This article discusses osteosynthesis in patients with femoral neck fractures. Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: In the PubMed database, the results of our search brought up 655 articles, whereas the results of our search on SagePub brought up 254 articles. The results of the search conducted for the last year of 2013 yielded a total 192 articles for PubMed and 89 articles for SagePub. In the end, we compiled a total of 33 papers, 21 of which came from PubMed and 12 of which came from SagePub. We included seven research that met the criteria. Conclusion: Non-pharmacological interventions that can be carried out are complementary therapies such as controlling eating patterns, doing relaxation and regular physical activity. Exercise is a strong stimulus to increase glucose input (glucose uptake) into muscle cells.