Eerdun Wurile (EW) is one of the most widely used traditional Mongolian medicines for stroke recovery. Previous studies revealed that EW regulates brain gene expression in a rat model of middle cerebral artery occlusion (MCAO). However, the fraction of active components and the specific genes regulated by such fractions have not been elucidated clearly. The study shows that the extracts of EW regulate the expression of genes involved in oxidative stress and apoptosis in rat pheochromocytoma (PC-12) cells. Hydrogen peroxide (H 2 O 2)-induced cell death was reversed by EW extracts, and reactive oxygen species (ROS) production was reduced, while superoxide dismutase (SOD) activity as well as catalase (CAT) activity increased significantly. Moreover, the expression of Bcl-2, PARP and NF-kB p65 was upregulated by EW extract, while Bax was downregulated. Similarly, caspase 9 and Jnk was remarkably downregulated by EW extracts. Significantly, EW extracts promoted the neurite outgrowth of PC-12 cells. Our data collectively suggested that EW contains active fractions that regulate the expression of genes involved in oxidative stress and cell apoptosis, which may contribute to the neural protection effect of EW.
The study that based on the topography map of Saihan campus , the Inner Mongolia normal university in 2003 , and combined with Sketchup each function , make Saihan campus become virtual three-dimensional simulate campus .
In the study we mapped and analyzed the land use/cover changes in Zheng Lanqi county by visual interpreting the 3 sets of Landsat TM and ETM remotely sensed images received in 1990, 2000 and 2005.The 6 broad types of land use/ cover were interpreted for the study area. Through analyzing land use/cover changes, our study indicated that the grassland and built-up area is dominant landscape in the study area.The grassland in the study area shrank 588.68km2 for urbanization and farmland cultivation for first periods. The unchanged land is 10639.75km2 and 10743.18km2 for the two periods (1990-2000 and 2000-2005), respectively. This indicated that the landscape conversion in second period became stable than that of first period, and environment is improved since 2000.
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