Aprepitant triple therapy was generally well tolerated; CR were greater with aprepitant, although not statistically significant. Pharmacokinetics suggest that the adult dosing regimen is appropriate for adolescents.

These results provide evidence that Bt allergens are distinct and have relatively low to moderate cross-reactivity with Dermatophagoides spp. allergens. Bt allergens should therefore be included in the diagnostic panel for the evaluation of allergic disorders in the tropics, and the development of new diagnostic and therapeutic strategies should include allergens of Bt.

Bioretention cells are an emerging low impact development technology that address urban stormwater runoff concerns. Field and column experiments were conducted to assess the efficacy of bioretention cells in cold conditions. Field experiments in a prairie environment demonstrated a significant decrease (91.5%) in effluent volumes compared to influent volumes. The majority (∼60%) of the runoff percolated to the surrounding soils or evapotranspirated. Cold condition performance significantly impacted high volume events and was characterized by significantly higher effluent volumes, significantly lower runoff storage, higher effluent peak flow rates, and longer peak delays. A partially frozen surface layer caused the changes in performance. Long-term simulation experiments on the columns indicated a significant decrease in saturated hydraulic conductivity over the first 4 equivalent years of operation, before levelling to a constant value.

Field and column experiments were conducted to test the ability of bioretention cells to improve urban runoff quality. The effects of cold climate conditions, media depth, long-term operation, and extreme loading were analyzed. Field experiments demonstrated significant decrease in contaminant mass, which was a function of the large runoff volume capture. Significant decreases in concentration for sediment (96%), biochemical oxygen demand (BOD, 8%), and total phosphorus (0.6%) were noted. Long-term simulation experiments demonstrated a decrease in effluent concentration over time, suggesting a dependence on media chemistry. Sediment and BOD capture remained high throughout the testing period. Media depth did not impact performance in laboratory experiments. Extreme loading experiments proved that the effluent concentration of contaminants was independent of the influent concentration. Cold climate conditions did not have a significant impact on performance in both field and column experiments.

A strained-modified, single-band, constant-potential three-dimensional model is formulated to study the dependence of electronic states of InAs/ GaAs quantum dots ͑QDs͒ on shape and size variation. The QD shapes considered are ͑i͒ cuboid, ͑ii͒ cylindrical, ͑iii͒ pyramidal, ͑iv͒ conical, and ͑v͒ lens shaped. Size variations include ͑i͒ QD volume ͑ii͒ QD base length, and ͑iii͒ QD height, taking into account aspect ratio variation. Isovolume QD shapes with narrow tips were found to have higher ground-state energies than those with broad tips, and this is attributed to the smaller effective volume. The volume, base length, and height dependencies were obtained and found to tally well with both experimental results and advanced calculations. Hence, upon growth parameter variation, this can provide an alternative to confirm whether the change to the size of the uncapped QDs implies a similar change to the capped ones. Ground-state energy as function of aspect ratio does not follow a monotonic trend. Owing to the competing effect of a decrease in base length and an increase in height, the energy trend exhibits a sharp decrease to an optimum aspect ratio, followed by gentle, almost linear increase. The optimum aspect ratio varies among shapes and is predicted to be smaller for shapes with broad tips. The effective volume ratio of both shapes ͑V eff,CUBOID / V eff,PYRAMID ͒ was determined, and found to vary with aspect ratio. Furthermore, a "cross-over" of lens-shaped QD from "lower energy" to "higher energy" group is predicted due to significant shape transition.