[structure: see text] The binding ability and self-assembly behavior of molecular interpenetration by newly synthesized mono[6-O-(4-formyl-phenyl)-beta-cyclodextrin has been investigated, revealing the formation mechanism of modified cyclodextrin from solution aggregation to solid linear polymeric supramolecules.

An inclusion complex formed by beta-cyclodextrin and quinine has been investigated in solution and in the solid state, in which the quinoline ring and the aliphatic ring locate in different hydrophobic cavities, respectively. The study on the inclusion geometry and weak interactions shows that the difference in conformation for this complex is a result of three main packing arrangement considerations, which can provide an ideal model mimicking enzyme-substrate interactions.

The title compound, C13H11N3O2, was prepared by the reaction of pyridine‐4‐carboxylic acid hydrazide and p‐hydroxy­benzaldehyde in ethanol. In the crystal structure, all non‐H atoms are coplanar, with an r.m.s. deviation of 0.096 Å. N—H⋯N, O—H⋯N and O—H⋯O inter­molecular hydrogen bonds stabilize the structure.

Key indicatorsSingle-crystal X-ray study T = 293 K Mean '(C±C) = 0.004 A Ê R factor = 0.056 wR factor = 0.165 Data-to-parameter ratio = 14.0For details of how these key indicators were automatically derived from the article, see A view of (I), showing the atom-numbering scheme. Displacement ellipsoids are drawn at the 30% probability level and H atoms are shown as small spheres of arbitrary radii. organic papers o146 Jing et al.