This 2014 review of Asian American psychology is the sixth review in the series. It includes 316 articles that met the inclusion criteria established by the past five annual reviews. Featured articles were derived from three sources: 137 were generated via the search term "Asian American" in PyscINFO, 111 were generated via a search for specific Asian American ethnic groups, and 32 were generated via author searches of articles that met the inclusion criteria. The top primary topic was health and health-related behaviors, the most frequently employed study design was crosssectional, and the most studied Asian American ethnic group was Chinese. This year's review includes information on the target population of the primary topic, the age range and developmental period of participants, and whether the study design was cross-sectional or longitudinal. It also identifies top authors and journals contributing to the 2014 annual review. These new features reveal that the most common target population of the primary topic was Correspondence concerning this article should be sent to Su Yeong Kim, Department of Human Development and Family Sciences, 108 E Dean Keeton St., Stop A2702, The University of Texas at Austin, Austin, TX 78712. su.yeong.kim@utexas.edu. HHS Public Access Author manuscriptAsian Am J Psychol. Author manuscript; available in PMC 2016 December 01. Published in final edited form as:Asian Am J Psychol. 2015 December ; 6(4): 291-332. doi:10.1037/aap0000031. Author Manuscript Author ManuscriptAuthor ManuscriptAuthor Manuscript youths; studies most commonly included emerging adults ages 18-25; cross-sectional study design was employed more often than longitudinal design; the top contributor to the 2014 review was Stephen Chen, who authored the highest number of papers included; and the Asian American Journal of Psychology generated the highest number of publications for this review. Keywords review; Asian Americans, 2014The annual review of Asian American psychology facilitates a comprehensive, year-to-year understanding of the field by summarizing the major research topics and methodology used in Asian American psychology. Comparison of multiple annual reviews reveals past, current, and emerging trends. Illuminating these trends can be informative for new and experienced scholars alike, who can utilize the reviews to synthesize past and current research. This will help them identify emerging trends in order to plan future research that will make a meaningful contribution to scholarship on Asian American psychology. The present annual review uses the format established by the past five annual reviews, with the addition of new features for future annual reviews to consider. Like past reviews, the current issue presents major trends by primary topic, methodological design, and participant characteristics (e.g., average age and ethnicity). This review contributes a developmental perspective by including age range and developmental period in our categorization of participants, and by considering cross-...

Vitamin A is required for normal body function, including vision, epithelial integrity, growth, and differentiation. All trans-retinoic acid (ATRA), a family member of vitamin A, has been explored in treating acute promyelocytic leukemia and other types of cancer. Dysregulated Wnt/β-catenin signaling and disrupted cadherin-catenin complex often contribute to colorectal malignancy. MED28, a mammalian Mediator subunit, is found highly expressed in breast and colorectal cancers. Our laboratory has also reported that MED28 regulates cell growth, migration, and invasion in human breast cancer cells. In the current study we investigated the effect of ATRA on MED28 and Wnt/β-catenin signaling in colorectal cancer. HCT116, HT29, SW480, and SW620, four human colorectal cancer cell lines representing different stages of carcinogenesis and harboring critical genetic changes, were employed. Our data indicated that regardless of genetic variations among these cells, suppression of MED28 reduced the expression of cyclin D1, c-Myc, and nuclear β-catenin, but increased the expression of E-cadherin and HMG box-containing protein 1 (HBP1) where HBP1 has been described as a negative regulator of the Wnt/β-catenin signaling. The reporter activity of an HBP1 promoter increased upon MED28 knockdown, but decreased upon MED28 overexpression. ATRA reduced the expression of MED28 and mimicked the effect of MED28 suppression in down-regulating Wnt/β-catenin signaling. Taken together, ATRA can reverse the suppressive effect of MED28 on HBP1 and E-cadherin and inactivate the Wnt/β-catenin pathway in colorectal cancer, suggesting a protective effect of ATRA against colorectal cancer. J. Cell. Physiol. 231: 1796-1803, 2016. © 2015 Wiley Periodicals, Inc.

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Increasing lines of evidence indicate that the biologically active form of vitamin D, calcitriol (1,25-dihydroxyvitamin D3), prevents cancer progression by reducing cell proliferation, increasing cell differentiation, and inhibiting angiogenesis, among other potential roles. Cancer cells in solid tumors preferably undergo the “Warburg effect” to support cell growth by upregulating glycolysis, and the glycolytic intermediates further serve as building blocks to generate biomass. The objective of the current study is to investigate whether calcitriol affects glucose metabolism and cell growth in human colorectal cancer cells. Calcitriol reduced the expression of cyclin D1 and c-Myc. In addition, calcitriol reduced the expression of glucose transporter 1 (GLUT1) and key glycolytic enzymes and decreased extracellular acidification rate but increased oxygen consumption rate in human colorectal cancer cells. In a subcutaneous HT29 xenograft NOD/SCID mouse model, the volume and weight of the tumors were smaller in the calcitriol groups as compared with the control group, and the expression levels of GLUT1 and glycolytic enzymes, hexokinase 2 and lactate dehydrogenase A, were also lower in the calcitriol groups in a dose-responsive manner. Our data indicate that calcitriol suppresses glycolysis and cell growth in human colorectal cancer cells, suggesting an inhibitory role of the biologically active form of vitamin D in colorectal cancer progression.

This work proposes a new Stereo Vision-Based SelfLocalization System (SVBSLS) for the RoboCup soccer humanoid league rules for the 2010 competition. The humanoid robot integrates the information from the pan/tilt motors and stereo vision to accomplish the self-localization and measure the distance of the robot and the soccer ball. The proposed approach uses the trigonometric function to find the coarse distances from the robot to the landmark and the robot to the soccer ball, and then it further adopts the artificial neural network technique to increase the precision of the distance. The statistics approach is also used to calculate the relationship between the humanoid robot and the position of the landmark for self-localization. The experimental results indicate that the localization system of SVBSLS in this research work has 100% average accuracy ratio for localization. The average error of distance from the humanoid soccer robot to the soccer ball is only 0.64 cm.