Odontogenic keratocysts (OKCs) are developmental odontogenic cyst of epithelial origin. Multiple OKCs are often associated with a syndrome, especially nevoid basal cell carcinoma syndrome. The present article presents a series of two nonsyndromic cases of multiple OKCs. The presence of multiple OKCs and their recurrence can be attributed to factors such as the friable cystic lining, and daughter cysts. However, a comprehensive evaluation of any patients reporting multiple cysts/OKCs always has to be undertaken and the syndromic association should be ruled out.