Low latency is highly desirable for cloud services. To achieve low response time, stringent timing requirements are needed for task scheduling in a large-scale server farm spanning thousands of servers. In this paper, we conduct an in-depth analysis for distributed Join-the-Idle-Queue (JIQ), a promising new approximation of an idealized task-scheduling algorithm. In particular, we derive semi-closed form expressions for the delay performance of distributed JIQ, and we propose a new variant of distributed JIQ that offers clear advantages over alternative algorithms for large systems.
Introduction: Non-invasive photothermal therapy (PTT) is a competitive treatment for solid tumors, while the efficacy is largely dependent on the effective retention of photothermal converters in tumor tissues.Methods: Herein, the development of iron oxide (Fe3O4) nanoparticle-loaded alginate (ALG) hydrogel platform for PTT of colorectal cancer cells is reported. Fe3O4 nanoparticles synthesized via coprecipitation method after reaction of 30 min have a small size (61.3 nm) and more suitable surface potential, and can mediate PTT under near-infrared (NIR) laser irradiation. The premix of Fe3O4 nanoparticles and ALG hydrogel precursors can be gelatinized by Ca2+-mediated cross-linking to form this therapeutic hydrogel platform.Results: The formed Fe3O4 nanoparticles can be effectively taken up by CT26 cancer cells and induce the death of CT26 cells in vitro under NIR laser irradiation because of their excellent photothermal property. In addition, Fe3O4 nanoparticle-loaded ALG hydrogels show negligible cytotoxicity at the studied concentration range, but can significantly kill cancer cells after PTT effect.Conclusion: This ALG-based hydrogel platform provides a valuable reference for subsequent in vivo studies and other related studies on Fe3O4 nanoparticle-loaded hydrogels.
The fluid distribution is considerably influenced by the reservoir homogeneity. This study analyzes carbonate reservoir heterogeneity and hydrocarbon accumulation processes in the Khasib reservoirs in AB oilfield in the Middle East to discuss factors controlling the distribution of fluid and the effects of this distribution on the productivity of single wells. The Khasib reservoirs in the AB oilfield show uniform vertical distributions, with a large difference in the longitudinal pore throats, and the upper part of the reservoir is better than the lower one. Because the hydrocarbon accumulation is multiphasic, the heterogeneity of crude oil is based on whether traps are formed in the early or late stage of source rock formation during accumulation. Moreover, the longitudinal physical differences in crude oil properties are mainly attributed to the longitudinal differences in the pore throats. The difference in the pore throat and physical properties of crude oil affords differences in the productivity of horizontal wells in different subzones.
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