Hemorrhagic complications during or after pelvic floor reconstructive surgery are rare. Mesh use and concomitant VH are two major surgical risk factors for hemorrhagic complications in pelvic floor reconstructive surgery.

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Electrochemical nitrogen reduction reaction (NRR) under ambient conditions offers an environmentally benign and sustainable alternative for NH3 synthesis. Exploring highly active and robust NRR electrocatalysts is one of the prerequisites for developing sustainable N2/NH3 cycle systems. In this work, a surface chemistry rich TiO2/CeO2 frame is developed for electrochemical NRR, which is composed of ultrathin TiO2 nanosheets supported with CeO2 nanoparticles. Its unique porous framework as well as formed plentiful oxygen vacancies (OVs) and hetero‐interfaces collectively facilitate the adsorption/activation of N2 and transfer of electrons and protons. The catalyst can attain a high NH3 yield rate of 8.8 μg h−1 mg−1cat. and a Faradaic efficiency of 6.8 % at −0.25 V versus reversible hydrogen electrode, comparable with other reported Ti‐based and OVs‐contained catalysts. Moreover, the TiO2/CeO2 can maintain high durability over repeated 20 cycles. Therefore, this work heralds a new paradigm of fabricating framework‐structured catalyst with enriched hetero‐interfaces and defects toward effective and sustainable NH3 synthesis.

Objectives To investigate the effects of livin on the Th2 immune response in airway allergic diseases (AAD) and explore the interaction among livin, GATA3, IL-4 in peripheral blood CD4+ T cells of AAD patients. Methods WT mice and livin KO mice were developed for model of AAD. Th2 cell levels in the lung tissues and spleen were assessed by flow cytometry. Also, it was assessed in the culture after exposing to livin inhibitor (Lp-15); the protein and mRNA levels of livin, GATA3 and IL-4 in peripheral blood CD4+ T cells isolated from patients with or without AAD were measured by real-time quantitative polymerase chain reaction (RT-qPCR) and Western blotting, respectively. Finally, Co-immunoprecipitation (Co-IP) was employed to identify the interaction between livin and GATA3. Results Compared with WT mouse, Th2 cell frequency in lung tissues and spleen was significantly decreased in livin KO mouse; after adding Lp-15, the differentiation from Naive CD4+T cells in spleen to Th2 cells was blocked; the protein and mRNA levels of livin, GATA3 and IL-4 in AAD group were higher than that in control group. The levels of livin were positively correlated with IL-4, and GATA3 was also positively correlated with IL-4 and livin. GATA3 was detected in the protein complex co-precipitated with livin antibody, and livin was also detected in the protein complex co-precipitated by GATA3 antibody. Conclusion Livin increases the expression of IL-4 and facilitates naive CD4+ T cells to differentiate into Th2 cells, which triggers airway allergy.

Despite the direct utilizing metal-organic frameworks (MOFs) as promising photocatalysts for H 2 O 2 production, their activity and selectivity are still undesirable owing to the insufficient active centers, weak visible-light absorption, and limited charge transfer. Herein, the Ce-doped Tibased MOFs MIL-125-NH 2 photocatalysts (Ce/TiMOFs) were synthesized by a facile impregnation-coordination method, during which the doped Ce species could not only extend the visible-light absorption edge but also provide new reactive sites for promoting the charge transfer and selectiv-ity of two-electron O 2 reduction. Interestingly, the optimal Ce/TiMOFs-0.010 achieved a rate of H 2 O 2 yield of 2464 μM h À 1 g À 1 with ~3.4-fold improvement compared to TiMOFs, attributed to the faster conversion rate of the main reactive oxygen intermediates ( * O 2 À ) and improved average transfer electron number. This work provides an effective strategy to optimize the photocatalytic performances of MOFs and expands the application of MOFs in the sustainable energy production field.