Glycosylation is ubiquitous throughout the central nervous system and altered following spinal cord injury (SCI). The glial scar that forms following SCI is composed of several chondroitin sulfate proteoglycans, which inhibit axonal regrowth. Cyclosporin-A (CsA), an immunosuppressive therapeutic, has been proposed as a potential treatment after SCI. We investigated CsA treatment in the spinal cord of healthy, contusion injured, and injured CsA-treated rats. Lectin histochemistry using fluorescently labeled lectins, SBA, MAA, SNA-I, and WFA, was performed to identify the terminal carbohydrate residues of glycoconjugates within the spinal cord. SBA staining decreased in gray and white matter following spinal cord injury, whereas staining was increased at the lesion site in CsA-treated animals, indicating an increase in galactose and N -acetylgalactosamine terminal structures. No significant changes in MAA were observed. WFA staining was abundant in gray matter and observed to increase at the lesion site, in agreement with increased expression of chondroitin sulfate proteoglycans. SNA-I-stained blood vessels in all spinal cord regions and dual staining identified a subpopulation of astrocytes in the lesion site, which expressed α-(2,6)-sialic acid. Glycosylation were altered in injured spinal cord treated with CsA, indicating that glycosylation and alteration of particular carbohydrate structures are important factors to consider in the examination of the environment of the spinal cord after injury.

‘Single’ women continue to experience stigma during pregnancy and mothering in the Republic of Ireland. This article explores the experiences of stigma of single women who were pregnant and mothering in Ireland between 1996 and 2010. The biographic narrative interpretive method (BNIM) was used to elicit biographical narratives. Analysis on both the lived experience of the women and the social context of the time created a ‘situated subjectivity’ in a sociocultural context. This article argues that despite large-scale positive social change before and during this period, single women’s pregnancy and motherhood continued to be to be stigmatised in Ireland. Women experienced this stigma in their everyday interactions. They negotiated stigma in their personal and social lives, employing strategies that drew on material and symbolic resources available to them. Social class, ethnicity and time were among factors that mediate the experience, but can also intersected in particular social locations to create a more stigmatised identity.

Recent studies of family life in Ireland have focused on changes in "traditional" family structures, including the increase in one-parent families. This article illustrates the impact dominant conceptions in Irish society that privilege the family based on marriage have on one-parent family policy. The authors focus on two key areas of social interaction associated with family lifeparenthood and (un)paid work-to identify both congruences and tensions between social policy and the needs of one-parent families. The article draws on interview and survey data collected in Galway in 2007 to show how existing welfare policies create some opportunities for those parenting alone while at the same time perpetuating inequalities within the gendered family context and across multiple generations.

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This paper introduces the use of new technologies and creative practices in teaching groupwork within two applied Irish postgraduate MA courses (Social Work and Community Development). By reflecting on experiences of teaching groupwork through the use of visual biographies, mask making, aural and video podcasting, the authors argue that creative teaching works to integrate experiential, practical and theoretical knowledge of groupwork. A more widespread adoption and evaluation of creative technologies in teaching groupwork to enhance student learning and affirm professional competencies is proposed.Keywords: social work; community development; creative technologies; podcasting; mask-making; visual biographies; group work; groupwork