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Nitrendipine-based antihypertensive therapy is particularly beneficial in older patients with diabetes and isolated systolic hypertension. Thus, our findings do not support the hypothesis that the use of long-acting calcium-channel blockers may be harmful in diabetic patients.

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I'ree M. A microassav for active and total renin concentration in htomani plasma based tiO antibodv trapping. Chitn (/hinm lAt-t 1980;101:5-15 12 Dusterdieck G(, McEllwee Mortality from coronary heart disease in civil servants in the lowest grade of employment has been found to be about three times that of men in the highest grade of employment. As part of an investigation ofthis finding several haemostatic variables were measured in a sample of 29 men in lower grades of employment and 45 men in higher grades. There was a significant difference in plasma fibrinogen concentrations between men in lower grades of employment and those in higher grades (mean 3 39 g/l v 2-95 g/l, respectively; p