The Banff 97 working classification refines earlier schemas and represents input from two classifications most widely used in clinical rejection trials and in clinical practice worldwide. Major changes include the following: rejection with vasculitis is separated from tubulointerstitial rejection; severe rejection requires transmural changes in arteries; "borderline" rejection can only be interpreted in a clinical context; antibody-mediated rejection is further defined, and lesion scoring focuses on most severely involved structures. Criteria for specimen adequacy have also been modified. Banff 97 represents a significant refinement of allograft assessment, developed via international consensus discussions.
Objective:To test the hypothesis that quantitative variation in eating behaviour traits shows a graded association with weight in children.Design:Cross-sectional design in a community setting.Subjects:Data were from 406 families participating in the Physical Exercise and Appetite in CHildren Study (PEACHES) or the Twins Early Development Study (TEDS). Children were aged 7 to 9 years (PEACHES) and 9 to 12 years old (TEDS).Measurements:Weights and heights were measured by researchers. BMI SD-scores were used to categorise participants into healthy-weight, overweight and obese groups, with an additional division of the healthy-weight group into higher- and lower-healthy-weight at the 50th centile. Eating behaviour traits were assessed with the Child Eating Behaviour Questionnaire (CEBQ), completed by the parent on behalf of their child. Linear trend analyses compared CEBQ sub-scale scores across the five weight groups.Results:Satiety Responsiveness/Slowness in Eating and Food Fussiness showed a graded negative association with weight, while Food Responsiveness, Enjoyment of Food, Emotional Overeating and Desire to Drink were positively associated. All effects were maintained after controlling for age, sex, ethnicity, parental education and sample. There was no systematic association with weight for Emotional Undereating.Conclusion:These results support the idea that approach-related and avoidance-related appetitive traits are systematically (and oppositely) related to adiposity, and not exclusively associated with obesity. Early assessment of these traits could be used as indicators of susceptibility to weight gain.
ObjectiveTo determine whether controlling parental feeding practices are associated with children’s adiposity and test the hypothesis that any associations are mediated by maternal perception of their child’s weight.MethodChildren aged 7-9 yrs (n=405) were weighed and measured at school as part of the Physical Exercise and Appetite in CHildren Study (PEACHES). Adiposity was indexed with BMI SD-scores. The Child Feeding Questionnaire (CFQ) was completed by 53% of mothers of participating children (n=213). Mothers reported whether they thought their child was overweight, normal weight or underweight, and rated their concern about future overweight on a 5-point scale.ResultsHigher child adiposity was associated with lower ‘pressure to eat’ and higher ‘restriction’ scores. Restriction increased linearly with maternal concern about overweight, and maternal concern about overweight fully mediated the association between child adiposity and restriction. Use of pressure increased as mothers perceived their child to be thinner, but perceived weight did not mediate the association between child weight status and maternal pressure to eat. Monitoring was not associated with child adiposity, maternal perception of weight or concern about overweight.ConclusionRestriction appears to be a consequence of mothers’ concern about their child becoming overweight rather than a cause of children’s weight gain. Pressure may be a more complex response that is influenced by the desire to encourage consumption of healthy foods as well as ensure adequate energy intake and appropriate weight gain.
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