This research was conducted at Maju Farmer's Group in Karangpasar Village, Tegowanu District, Grobogan Regency. This research aimed to 1) Analyze factors that influence the production of corn farming varieties Pioneer 36 and NK 212, 2) Analyze economic efficiency of corn farming varieties Pioneer 36 and NK 212 and 3) Analyze comparation in economic efficiency of corn farming varieties Pioneer 36 and NK 212. The research used survey method. The sampling used accidental sampling with Slovin collections of 62 respondents consisted of 31 respondents of Pioneer 36 and NK 212. The data analysis used multiple regression with function of Cobb-Douglass model, calculation of economic efficiency and comparative economic efficiency of varieties Pioneer 36 and NK 212. The results showed that 1) Input Pioneer 36 consists of land area, seeds and fertilizers had significantly affected to production, meanwhile input NK 212 consists of land area, fertilizer and labor had significantly affected to production. 2) The production factor of Pioneer 36 consists of land area, pesticides and labor are not economically efficient, meanwhile the production factor of seed and fertilizer are not economically efficient. The production factor of NK 212 consists of seeds, pesticides and labor in NK 212 varieties are not economically efficient, meanwhile the production factor of land area and fertilizer inputs are not economically efficient. 3) There are significantly different of economic efficiency of varieties Pioneer 36 and NK 212 that consists of land area, seeds, pesticides and labor, meanwhile the economic efficiency of fertilizer were not significantly different.