Se presentan los resultados del análisis de una parte del conjunto cerámico recuperado en el Pucará de Tilcara durante las excavaciones de Ambrosetti y Debenedetti, desarrolladas a inicios del siglo XX. El estudio estilístico de estas piezas, conservadas en las colecciones de dos museos de la Universidad de Buenos Aires, permitió caracterizar la dinámica de los procesos sociopolíticos que llevaron a la intensa circulación de objetos durante la época prehispánica tardía. A su vez, a partir de la contextualización de piezas incaicas, procedentes de distintas provincias del Tawantinsuyu, se determinaron pautas de consumo diferencial. Se plantea que el uso de diversas categorías de bienes estuvo vinculado a la función social y económica que cumplieron distintos grupos de personas en el Pucará.Palabras claves: ocupación inca, colecciones museológicas, distribución cerámica intrasitio, consumo diferencial.This paper presents the results of an analysis of part of the ceramic assemblage found at the Pucará of Tilcara during Ambrosetti's and Debenedetti's excavations, that took place at the beginning of the twentieth century. The stylistic study of this pottery, found in the collections of two museums at the Universidad de Buenos Aires, allows a characterization the dynamics of the social and politic processes that encouraged the circulation of objects during late prehispanic times. The location of inca pieces that came from different provinces of Tawantinsuyu demonstrate different consumption patterns. The paper concludes that the use of special categories of goods was tied to the social and economic role that different human groups had at the Pucará.
Atopic asthma results from airway inflammation triggered by an environmental allergen. Symptoms include wheezing, dyspnea and cough, airway narrowing and/or hyperresponsiveness to several inhaled stimuli. Inflammation develops in a two-phase fashion. The first phase after exposure to the allergen consists of degranulation and release of both histamine and other stored preformed inflammatory mediators as well as newly synthesized ones, including cytokines, all of which increase mucus secretion and smooth muscle contraction. The second phase occurs later and lasts longer; it is due to different molecules: several cytokines and chemokines, arachidonic acid derivatives, enzymes such as metalloproteinases and cell adhesion molecules. Cytokines are key players in the chronic inflammation in asthma patients, but details on their role and interactions still remain undetermined. Recent evidence suggests that allergic asthma is a multifaceted condition actively controlled by effector as well as regulatory T cells (Tregs). T helper (Th) 2 cells and Th17 cells increase airway inflammation, while Tregs are anti- inflammatory. Cytokines are involved in the development and activation of all T cell subpopulations. They are also involved directly or indirectly in most approaches to asthma treatment. Several cytokines have been tested as therapeutic targets and some of the currently used therapies like corticosteroids, beta agonists and allergen immunotherapy affect cytokine production. The increased knowledge on cytokine interplay and lymphocyte subsets should generate new therapeutic strategies in the near future.
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