Hyaluronic acid fillers did not show any fungal or bacterial contamination after being opened and stored at room temperature in nonaseptic conditions. The possibility of reusing the remaining portion of the material in the syringe can be safe and economically viable.

Nevus sebaceous is the most common type of organoid epidermal nevus, often located on the face, following the Blaschko's lines and with alterations in the ipsilateral central nervous system. Distinct disorders can be distinguished by the type of association with epidermal nevus. Schimmelpenning-Feuerstein-Mims syndrome is a rare multisystem disorder characterized by sebaceous nevus associated with extracutaneous abnormalities affecting the brain, eyes and bones. We report the case of an 8-year-old female patient with a yellowish verrucous plaque on the left temporal area extending ipsilaterally to the cervical region, combined with cicatricial alopecia, periocular nodule, and epibulbar tumors.

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This study verified the effects of fish oil n-3 fatty acids on the inflammatory profile, redox state, adhesion molecules and impact on the life quality of patients with psoriasis. Forty patients with chronic plaque psoriasis were randomized to one of two groups: fish oil group (n=20), which received 3g/d of fish oil n-3 fatty acids (10 capsules) and control group (n=20), which maintained their usual diet. Inflammatory biomarkers, nitro-oxidative stress including lipid hydroperoxides (LOOH) in plasma and red blood cells, advanced oxidation protein products (AOPP), nitric oxide metabolites (NOx), sulfhydryl groups and total radical-trapping antioxidant parameter (TRAP) were measured as well as adhesion molecules and plasminogen activator inhibitor type-1; Psoriasis Area Severity Index (PASI) and Dermatology Life Quality Index (DLQI) were also evaluated. All parameters were measured at baseline and after 90 days of supplementation. The group receiving fish oil showed decreased erythrocyte sedimentation rate (ESR) (p=0,007), LOOH in red blood cells (p=0,048), AOPP (p=<0,001) and increased sulfhydryl groups (p=0,001), TRAP (p=0,010) and DLQI. There were not significant results in PASI, adhesion molecules, PAI-1, NOx, and plasma LOOH. Inter-group changes (p<0.05) verified an improvement in the patient's life quality measured by DLQI, a decrease in AOPP and an increase in SH. The present study indicated that ingestion of capsules of n-3 fish oil fatty acids was able to improve life quality, to reduce inflammatory status, to decrease lipid peroxidation and protein oxidation, and to increase the total antioxidant capacity in patients with psoriasis.