BACKGROUND AND OBJECTIVES:There are few studies evaluating the effects of physiotherapy with multidimensional instruments on cancer pain. The objective of this study was to evaluate the effects of physiotherapy on pain and functional capacity in hospitalized cancer patients. METHODS: This is a quasi-experimental study including 40 participants with a mean age of 51±18 years assessed before and after physiotherapy interventions, using the verbal numerical rating scale, the McGill Pain Questionnaire -Short Form, the International Physical Activity Questionnaire, the Sit-to-Stand test, and the Eastern Cooperative Oncology Group questionnaire for functional capacity evaluation. The participants were classified according to the number of performed sessions: group 1≤ 5 sessions (n=25) and group 2 ≥ 6 sessions (n=15). RESULTS: There was a reduction in cancer pain measured by sensory (p=0.02) and mixed descriptors (p=0.05) of the McGill questionnaire as well as by the numerical visual scale (p=0.03) in patients who performed at least six physiotherapy sessions. There was a significant correlation (r=0.81; p<0.001) between the reduction in pain measured by the numerical visual scale and the reduction in pain measured by the Total McGill questionnaire.