During the past 12 years, 19 patients have presented themselves with enlargement of the supraclavicular lymph nodes as the initial manifestation of previously unrecognized prostatic carcinoma. Of the 19 patients, 18 had enlargement of the left supraclavicular lymph nodes, and one had enlargement of those on the right side. This study group was compared with a control group of 100 consecutive previously untreated patients exhibiting the typical signs and symptoms of prostatic carcinoma. The histologic picture in both the lymph nodes and prostate gland of the study group was that of a less well‐differentiated carcinoma than was usually observed in the control group. The disease should, therefore, be considered when metastatic adenocarcinoma is discovered in the supraclavicular lymph nodes, usually those on the left, of men over 45 years of age. Prostatic carcinoma appearing initially as metastases in supraclavicular lymph nodes does not differ significantly in its response to therapy or survival from prostatic carcinoma manifested by the typical clinical features.

A validation study proved the value of electrical impedance scanning as a noninvasive technique for detection of melanoma lesions of the trunk and extremities, specifically, of in situ and thin type. In addition, image analysis was shown to be a valuable, complementary procedure. New parameters should be designed to optimize the performance of electrical impedance scanning for melanomas of the head and neck.