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L La at te e r re ec cu ur rr re en nc ce e o of f W We eg ge en ne er r' 's s g gr ra an nu ul lo om ma at to os si is s p pr re es se en nt ti in ng g a as s s so ol li it ta ar ry y u up pp pe er r l lo ob be e p pu ul lm mo on na ar ry y m ma as ss s Eight years previously, a first episode of WG involving the upper airways and kidneys, but not the lungs, had been successfully treated with prednisolone and cyclophosphamide, which could be stopped after 2 yrs. The antineutrophil cytoplasmic antibody titres (anti-protease 3), which had been very high during the first disease episode, failed to predict the recurrence.