Constance J. Ashley scite author profile

Effects of debrisoquin on the human platelet have been characterized in vivo and in vitro.The drug inhibits the uptake of serotonin by competing for a common transport process, interferes with the storage of serotonin within this cell, and inhibits platelet monoamine oxidase (MAO) activity. Similarities between the platelet and adrenergic neuron suggest that the platelet may serve as a convenient model for the neuron.

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Stereoisomeric relationships among anti-inflammatory activity, inhibition of platelet aggregation, and inhibition of prostaglandin synthetase

Gaut

Baruth

Randall

et al. 1975

Prostaglandins

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An improved competitive protein binding assay for 1,25-dihydroxyvitamin D

Mallon

Hamilton

Nauss-Karol

et al. 1980

Archives of Biochemistry and Biophysics

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Variable responses of human platelets to synthetic platelet activating factor and their modification by epinephrine

Tsien

Ashley

Sheppard

1982

Thrombosis Research

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