The aim of this study was to develop a delivery system for polyphenols from an extract of Echinacea purpurea leaves, based on liposomes. Liposomes loaded with Echinacea purpurea were prepared and characterized in terms of entrapment efficiency, size, polydispersity index, stability and release behavior. Results showed good entrapment efficiency, small sizes, low polydispersity index and good stability over 90 days at 4oC. Also, the liposomal formulations presented reduced burst release and slow release of polyphenols compared with free extract. Therefore, liposomes offer a great potential in the development of drug delivery systems for polyphenols.

The aim of this paper was the design and evaluation of delivery system for Armoracia rusticana leaves extract with the purpose to use such systems in food or cosmetic field. Liposomes loaded with Armoracia rusticana were prepared by film hydration method and presented good entrapment efficiency, nano-sizes ([150 nm), low polydispersity index and good stability over 90 days at 4oC. In vitro drug release study showed the ability of liposomes to provide slow release of extract with reduced burst effect compared to free extract. These promising results suggest that liposomes could be exploited as carriers for herbal ingredients.

Industrial hemp (Cannabis sativa L.) is a source of fibers, oil and valuable secondary metabolites. Regarding phenolic compounds, it has to be noted that the plant biosynthesizes molecules with various pharmacological benefits. The aim of this study was to prove the cytotoxic potential of hemp polar and non-polar fractions against two cancer cell lines (BT-20 and U87). The study revealed the potential antitumor activity of industrial hemp selective fractions but a correlation between polyphenols content and the cytotoxic effect could not be established.