The primary objective of this study was to describe our experience with the conservative treatment of early-stage cervical cancer (stages IA1, IA2, and IB1) with radical vaginal trachelectomy (RVT) and laparoscopic pelvic lymphadenectomy. This retrospective observational case series included 36 patients with early cervical cancer. Radical trachelectomy and laparoscopic pelvic lymphadenectomy were performed as described by D. Dargent in 32 of these cases. Oncologic, reproductive, and obstetric outcomes were observed subsequently over a median period of 42 (24-96) weeks. A total of 32 RVTs were preformed with a mean operating time of 117±22.8 (77-167) minutes and an average blood loss of 486 mL (150-800 mL). All obtained resection margins were negative for cancer. Lymphovascular space invasion was noted in 11 (30.55 %) of the cases. No recurrences occurred during the study period. Seven (17.8 %) patients were able to become pregnant postoperatively, five of whom delivered healthy infants near term. Radical vaginal trachelectomy with laparoscopic pelvic lymphadenectomy appears to be a safe therapeutic option for fertility preservation in young women with early cervical cancer.

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Introduction: Despite the success of early detection of mammary neoplasms and the application of an aggressive therapy, this pathology continues to be a clinical problem. Mortality associated with breast cancer is directly proportional to cell invasion and the presence of metastases. Tumor cells within a breast tumor may be present as secondary determinations and present a spine and bone-related tropism. Material and method: Analysis of articles published in the literature to observe the association between the presence of bone metastases at the time of diagnosis of breast cancer and during the oncological monitoring period according to staging. Results: Approximately 15% of the patients with stage I - III breast cancer have bone metastases during the first 60 months after surgery. Approximately 50% of the patients who had metastases presented as a bone location in oncological monitoring. The most common bone metastases are spine, ribs, pelvis, and long bones. Conclusions: Breast neoplasm has a distinct metastatic pattern with bone skeleton as the predominant site. Approximately 65 to 75% of the patients with invasive breast cancer develop bone metastases. For this reason, oncological monitoring should take into account the early identification of these secondary locations.

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